Human disease in Europe caused by a granulocytic Ehrlichia species.

Journal of Clinical Microbiology
M PetrovecJ S Dumler

Abstract

Human granulocytic ehrlichiosis (HGE) was recently described in North America. It is caused by an Ehrlichia species closely related to Ehrlichia phagocytophila and Ehrlichia equi, recognized to infect mostly ruminants and horses, respectively. The vector in North America is the tick Ixodes scapularis, which is also the vector of the Lyme disease agent, Borrelia burgdorferi. Previous serologic studies in patients with a diagnosis of Lyme borreliosis indicate that HGE may exist in Europe. We report the first documented case of HGE in Europe. The diagnosis was established by seroconversion to E. equi and the HGE agent and by PCR with sequence analysis of the gene encoding the HGE agent 16S rRNA. Interestingly, the patient presented with a self-limited but moderately severe illness. Thus, European physicians need to be aware that HGE exists in Europe and that the diagnosis should be considered in febrile patients with tick bites in areas where Lyme disease is endemic.

References

Sep 7, 1991·Lancet·J D MoraisF Bacellar
Dec 1, 1991·Journal of Clinical Microbiology·B E AndersonK H Wilson
Apr 2, 1987·The New England Journal of Medicine·K MaedaJ E McDade
Nov 4, 1995·Lancet·D PierardS Lauwers
Dec 2, 1995·Lancet·K J SumptionB A Dale
Sep 16, 1995·Lancet·P BrouquiD Raoult
Mar 1, 1994·Journal of Clinical Microbiology·S M ChenD H Walker
Apr 6, 1996·Lancet·G P WormserM Aguero-Rosenfeld
Jul 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·F StrleR N Picken
Jun 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M M PickenF Strle
Oct 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J S BakkenB E Kristiansen
Dec 1, 1996·Annals of Internal Medicine·M E Aguero-RosenfeldJ S Dumler

❮ Previous
Next ❯

Citations

Sep 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J S Bakken, J S Dumler
Jan 4, 2001·Clinical and Diagnostic Laboratory Immunology·P BrouquiD Raoult
May 28, 2002·Scandinavian Journal of Infectious Diseases·Anneli BjöersdorffIngvar Eliasson
Jun 14, 2003·Vector Borne and Zoonotic Diseases·Edward A Belongia
Sep 5, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·V RemyP Brouqui
Jun 5, 2003·Wiener klinische Wochenschrift·Gernot WalderPeter Lechleitner
Apr 21, 2007·Epidemiology and Infection·R M VorouS Tsiodras
Dec 18, 2009·Expert Review of Anti-infective Therapy·Paul HeymanAnna Papa
May 13, 2010·Acta Veterinaria Hungarica·Snezana TomanovićLjubisa Stanisavljević
Oct 30, 2010·Vector Borne and Zoonotic Diseases·Emina DurmišiTatjana Avšič-Županc
Sep 20, 2011·Vector Borne and Zoonotic Diseases·Melina KachrimanidouAnna Psaroulaki
Oct 2, 2014·Emerging Infectious Diseases·Kye-Hyung KimMyoung-don Oh
Jul 17, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·N PusterlaH Lutz
Sep 8, 1998·Scandinavian Journal of Infectious Diseases·A M LebechD H Persing
May 9, 2002·Emerging Infectious Diseases·Robert F MassungThomas N Mather
Mar 10, 2001·Scandinavian Journal of Infectious Diseases·U KarlssonB Christensson
Apr 30, 2003·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Johanna MäkinenMatti K Viljanen
Jul 16, 2003·Annals of the New York Academy of Sciences·Friederike D Von LoewenichChristian Bogdan
Dec 2, 2005·Emerging Infectious Diseases·Norio OhashiToshiyuki Masuzawa
Dec 19, 2001·Emerging Infectious Diseases·A BjöersdorffB Olsen
Sep 19, 2009·Journal of Veterinary Internal Medicine·D D CarradeJ E Sykes
Dec 1, 2006·Annals of the New York Academy of Sciences·Eugenio LilliniManuela Scarpulla
Aug 2, 2011·Asian Pacific Journal of Tropical Medicine·Lijuan ZhangShuxia Yang
Aug 18, 2009·Expert Review of Anti-infective Therapy·Rachael J ThomasJason A Carlyon
Jun 10, 2008·The Pediatric Infectious Disease Journal·Anna PsaroulakiYannis Tselentis
Sep 1, 2015·Frontiers in Cellular and Infection Microbiology·Thibaud DugatNadia Haddad
Dec 22, 1999·Equine Veterinary Journal·K ArturssonE O Engvall
Sep 7, 2002·DNA and Cell Biology·Robert F MassungAsiya Gusa
Sep 3, 2002·Clinical and Diagnostic Laboratory Immunology·Hyung-Yong KimYasuko Rikihisa
Oct 17, 2006·Clinical Microbiology Reviews·Stephen J SwansonEdward A Belongia
Mar 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P Parola, D Raoult

❮ Previous
Next ❯

Related Concepts

Related Papers

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
J S BakkenB E Kristiansen
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
J R Blanco, José Antonio Oteo
© 2021 Meta ULC. All rights reserved