Human endogenous retroviruses: friend or foe?

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
Robin A Weiss

Abstract

The integration of proviral DNA into host chromosomal DNA as an obligatory step in the replication cycle of retroviruses is a natural event of genetic recombination between virus and host. When integration occurs in cells of the germ line, it results in mendelian inheritance of viral sequences that we call endogenous retroviruses (ERV) and HERV for humans. HERVs and host often establish a symbiotic relationship, especially in the placenta and in pluripotent embryonic stem cells, but HERVs occasionally have deleterious consequences for the host. This special issue of APMIS features the fascinating relationships between HERV and humans in health and disease.

References

May 1, 1990·Virology·M A Sommerfelt, R A Weiss
Dec 1, 1971·The Journal of General Virology·L N PayneR A Weiss
Sep 2, 1999·Current Biology : CB·M BarbulescuJ Lenz
Jun 26, 2001·Genome Biology·D J Griffiths
Oct 15, 2003·Proceedings of the National Academy of Sciences of the United States of America·Sandra BlaiseThierry Heidmann
Mar 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Robert BelshawMichael Tristem
Apr 15, 2004·Genomics·C A HervéP J W Venables
Oct 13, 2004·Retrovirology·Palle VillesenFinn Skou Pedersen
Jul 11, 2006·Nature·Rachael E TarlintonPaul R Young
Sep 19, 2006·Proceedings of the National Academy of Sciences of the United States of America·Kathrin A DunlapThomas E Spencer
Oct 5, 2006·Retrovirology·Robin A Weiss
Jan 30, 2007·PLoS Pathogens·Young Nam Lee, Paul D Bieniasz
Oct 16, 2008·Cell·John L Goodier, Haig H Kazazian
Mar 10, 2009·Nature·Daniel Wolf, Stephen P Goff
Jun 30, 2009·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Juliette GimenezFrançois Mallet
Jan 16, 2010·Nature·Helen M RoweDidier Trono
Dec 2, 2010·Retrovirology·Christine A Kozak
Dec 3, 2010·PLoS Genetics·Aris Katzourakis, Robert J Gifford
Apr 16, 2011·Reproductive Sciences·Amandine VargasBenoit Barbeau
Nov 5, 2011·Reviews in Medical Virology·Philip E PellettRaymund R Razonable
Jan 18, 2012·Retrovirology·Antoinette C van der Kuyl
Mar 17, 2012·Nature Reviews. Genetics·Cédric Feschotte, Clément Gilbert
May 9, 2012·Nature Reviews. Microbiology·Jonathan P Stoye
May 25, 2012·Mobile DNA·Rita RebolloDixie L Mager
Aug 18, 2012·Nature Reviews. Cancer·Peter K Vogt
Aug 22, 2012·Annual Review of Genetics·Rita RebolloDixie L Mager
Oct 5, 2012·Genome Research·Julien MeunierHenrik Kaessmann
Oct 30, 2012·Nature·George R YoungGeorge Kassiotis
Jan 23, 2013·Genome Biology and Evolution·Katja SchmittJens Mayer
Feb 12, 2013·Nature Genetics·Edward B ChuongJulie C Baker
May 3, 2013·Journal of Virology·Claudia Sánchez-San MartínMargaret Kielian
May 21, 2013·Science·Robin A Weiss, Jonathan P Stoye
Jul 19, 2013·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·George R YoungGeorge Kassiotis
Jul 19, 2013·Journal of Virology·Onyinyechukwu UchimeMargaret Kielian

❮ Previous
Next ❯

Citations

Aug 4, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·R Michael RobertsLaura C Schulz
Dec 17, 2016·Mobile DNA·Artem Babaian, Dixie L Mager
Jul 27, 2017·The New England Journal of Medicine·Haig H Kazazian, John V Moran
Jul 20, 2018·Open Biology·Gabriela O BodeaGeoffrey J Faulkner
Mar 9, 2021·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Maiken Kruse Kristensen, Tove Christensen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved