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Human erythrocyte glutathione reductase: chemical mechanism and structure of the transition state for hydride transfer

Biochemistry

Sep 3, 1991

W L Sweet, J S Blanchard

PMID: 1888731

Abstract

Kinetic parameters and primary deuterium kinetic isotope effects for NADH and five pyridine nucleotide substrates have been determined at pH 8.1 for human erythrocyte glutathione reductase. DV/KNADH and DV are equal to 1.4 and are pH independent below pH 8.1, but DV decreases to 1.0 at ...read more

Mentioned in this Paper

Tritium
GSR
Glutathione Reductase
Deuterons
Oxidation-Reduction
Erythrocytes
Hydrogen-Ion Concentration
Respiratory Chain
Paper Details
References
  • References25
  • Citations14
123
  • References25
  • Citations14
12

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Human erythrocyte glutathione reductase: chemical mechanism and structure of the transition state for hydride transfer

Biochemistry

Sep 3, 1991

W L Sweet, J S Blanchard

PMID: 1888731

DOI:

Abstract

Kinetic parameters and primary deuterium kinetic isotope effects for NADH and five pyridine nucleotide substrates have been determined at pH 8.1 for human erythrocyte glutathione reductase. DV/KNADH and DV are equal to 1.4 and are pH independent below pH 8.1, but DV decreases to 1.0 at ...read more

Mentioned in this Paper

Tritium
GSR
Glutathione Reductase
Deuterons
Oxidation-Reduction
Erythrocytes
Hydrogen-Ion Concentration
Respiratory Chain

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

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Paper Details
References
  • References25
  • Citations14
123
  • References25
  • Citations14
12
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