PMID: 7150660Dec 17, 1982

Human fibrinogen gel formed by the action of a cell surface polysaccharide obtained from a Staphylococcus

Biochimica Et Biophysica Acta
Y UsuiK Yoshida


An alkali-stable polysaccharide (called compact-colony forming active substance; substance 1) obtained from the cell surface of a strain of Staphylococcus epidermidis caused gel formation of human fibrinogen, with no release of fibrinopeptides. Substance 1 possessed neither esterase nor caseinolytic activities; no inhibition of gel formation was shown by dinitrofluorophosphate. Heparin and galactose prevented gel formation of fibrinogen with substance 1. With the addition of early- and late-fibrinogen or fibrin degradation products into the fibrinogen sample, no prolongation of the gel formation time was observed. This substance is, therefore, assumed to nonenzymatically induce gel formation with fibrinogen, a process resembling paracoagulation.


Jan 1, 1977·Journal of General Microbiology·K YoshidaY Minegishi
Nov 1, 1967·The Journal of Experimental Medicine·B LipinskiJ Jeljaszewicz
Jun 1, 1972·The Journal of Infectious Diseases·W HryniewiczJ Jeljaszewicz
Apr 25, 1980·Biochimica Et Biophysica Acta·K K Karhi, C G Gahmberg
Mar 1, 1994·Avian Pathology : Journal of the W.V.P.A·L A DevrieseE Uyttebroek

Related Concepts

Galactose Measurement
Fibrinogen Assay
Unspecified Staphylococcus Infection in Conditions Classified Elsewhere and of Unspecified Site
Genus staphylococcus
Fibrin-fibrinogen Split Products Assay
Polysaccharides, Bacterial
Peptide Fragments

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