PMID: 8964132Mar 1, 1996Paper

Human gallbladder pressure and volume: validation of a new direct method for measurements of gallbladder pressure in patients with acute cholecystitis

Clinical Physiology
L BorlyJ G Stage

Abstract

Increased gallbladder (GB) pressure is probably a part of the pathogenesis of acute cholecystitis, and measurements of GB pressure might therefore be of interest. The aim of this study was to validate a microtip pressure transducer for intraluminal GB pressure measurements. In vitro precision and accuracy was within 0.2 mmHg, (SD) and 0.6 +/- 0.1 mmHg (mean +/- SD), respectively. Pressure rise rate was 24.8 +/- 5.5 mmHg s-1. Zero drift was in the range 0.3 +/- 0.4 to 0.8 +/- 0.9 mmHg (mean +/- SD). GB pressure was investigated in 16 patients with acute cholecystitis treated with percutaneous ultrasonically guided cholecystostomy. Basal intraluminal GB pressure was 8.9 mmHg (2.1-12.2 mmHg; n = 9, open cystic duct) and 1.8 and 5.8 mmHg (n = 2, closed cystic duct). There was no significant difference between two different measurements in the same patients (n = 5). The pressure was significantly influenced by respiration (n = 8) and the pressure seems to be higher in the sitting position than in the supine position (n = 5). Cystic duct opening pressure was 10.4, 11.2 and 16.8 mmHg (n = 3). Pressure-volume responses showed that the GB up to a certain volume could accommodate increases in intraluminal volume with only slight changes ...Continue Reading

References

Jun 1, 1976·The American Journal of Physiology·J Ryan, S Cohen
Jan 1, 1991·Digestive Diseases·P Funch-Jensen, S S Sørensen
Aug 1, 1990·AJR. American Journal of Roentgenology·W J Dodds
Jan 1, 1990·Scandinavian Journal of Gastroenterology. Supplement·A TorsoliM Cicala
Aug 1, 1987·Journal of Neurosurgery·R C OstrupM H Zornow
Mar 1, 1980·American Journal of Surgery·A Csendes, A Sepulveda
Jul 31, 1926·The Journal of Experimental Medicine·P D McMaster, R Elman

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Citations

Mar 27, 2013·Journal of the Mechanical Behavior of Biomedical Materials·W G LiX Y Luo
Aug 3, 2014·Journal of Biomaterials Applications·Kevin M LewisHeinz Gulle
Nov 26, 2010·Annals of Biomedical Engineering·W G LiN Bird
Oct 6, 1998·Scandinavian Journal of Gastroenterology·H V MiddelfartP Funch-Jensen
Jun 29, 2021·Computer Methods in Biomechanics and Biomedical Engineering·Alex G KuchumovOleg Ivanov

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