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Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma

PloS One

Aug 4, 2009

Illya TietzelRey A. Carabeo

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Abstract

Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory cytokine interferon-gamma. IFN-gamma-inducible murine p47 GTPases have been demonstrated to function in resistance to chlamydia infection in vivo and in vitro. Because the human genome does not encode...read more

Mentioned in this Paper

Transfection
DNA Sequence
Vesicular stomatitis virus
GTP-Binding Proteins
guanylate
Interferon-gamma Receptor Binding Activity
Species
Interferon
Chlamydia trachomatis
Isoprenylation
Paper Details
References
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    • Citations34
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  • Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma

    PloS One

    Aug 4, 2009

    Illya TietzelRey A. Carabeo

    PMID: 19652711

    DOI: 10.1371/journal.pone.0006499

    Abstract

    Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory cytokine interferon-gamma. IFN-gamma-inducible murine p47 GTPases have been demonstrated to function in resistance to chlamydia infection in vivo and in vitro. Because the human genome does not encode...read more

    Mentioned in this Paper

    Transfection
    DNA Sequence
    Vesicular stomatitis virus
    GTP-Binding Proteins
    guanylate

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    References
    • References41
    • Citations34
    • References41
    • Citations34
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