PMID: 8941664Dec 1, 1996Paper

Human hair follicle regeneration following amputation and grafting into the nude mouse

The Journal of Investigative Dermatology
C A JahodaK A Horne

Abstract

In this study we investigated the capacity of the human hair follicle to regenerate a fiber-forming bulb after its amputation. We removed the bases from terminal follicles from a variety of sites and transplanted the follicles onto athymic mice, either still attached to a skin graft or as subcutaneous implants of individual follicles. External hair growth was observed on the skin grafts, and histology of the follicles revealed restoration of dermal papillae and follicle bulb structures. This result suggests that the capacity of hair follicles to regenerate their lower structures after removal, which was first demonstrated on whisker follicles, may be a general phenomenon. It emphasizes the importance of specific cellular subpopulations within the follicle and the role of dermal-epidermal interactions in adult follicle activities.

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May 1, 1979·The Journal of Investigative Dermatology·M InabaC McKinstry
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Citations

Jun 15, 1999·Medical & Biological Engineering & Computing·S T Boyce
Mar 6, 2008·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Susan StevensonM Julie Thornton
Dec 12, 2007·Experimental Dermatology·Jizeng QiaoJeff Teumer
Aug 22, 2008·Dermatologic Therapy·Kevin J McElwee
Oct 23, 2013·Cornea·Masatoshi HirayamaTakashi Tsuji
Dec 27, 2019·Stem Cells Translational Medicine·Ana Rita Castro, Elsa Logarinho
Feb 22, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Qian JiangeSun Wei
Jan 26, 2007·Journal of the Royal Society, Interface·Anthony D Metcalfe, Mark W J Ferguson
Sep 19, 2009·Regenerative Medicine·Jizeng QiaoJeff Teumer
May 31, 2012·Scientific Reports·Kyosuke AsakawaTakashi Tsuji
Jun 19, 2013·Cell Transplantation·Cinzia Maria ChinniciPier Giulio Conaldi
Apr 16, 2020·Journal of Tissue Engineering and Regenerative Medicine·Irit VahavSusan Gibbs
Jan 12, 2001·Physiological Reviews·K S Stenn, R Paus
Jan 1, 2012·Cells·Xanthe L Strudwick, Allison J Cowin
Apr 14, 2016·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Azar Z AsgariRodney D Sinclair
Aug 9, 2001·Experimental Dermatology·C A JahodaK A Horne
Nov 20, 2012·Tissue Engineering. Part B, Reviews·Panagiotis Mistriotis, Stelios T Andreadis
Mar 14, 2002·Lasers in Surgery and Medicine·E V Ross
Nov 27, 2020·Frontiers in Cell and Developmental Biology·Elena I Morgun, Ekaterina A Vorotelyak
Feb 18, 2021·Signal Transduction and Targeted Therapy·Shuaifei JiXiaobing Fu
Jan 5, 2002·The Journal of Investigative Dermatology. Symposium Proceedings·T HashimotoY Ueyama
Dec 25, 2004·Differentiation; Research in Biological Diversity·Ralf Paus, Kerstin Foitzik
Apr 13, 2007·The Journal of Investigative Dermatology·Ritsuko EhamaJiro Kishimoto
Dec 22, 2009·Journal of Dermatological Science·Chao-Chun Yang, George Cotsarelis
Jan 1, 2007·Organogenesis·K StennK Washenik
Dec 31, 2010·The Journal of Investigative Dermatology·James M WatersAllison J Cowin
Mar 17, 2011·The Journal of Investigative Dermatology·Maria I Morasso

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