Human immunodeficiency virus type 1-specific immunity after genetic immunization is enhanced by modification of Gag and Pol expression

Journal of Virology
Y HuangG J Nabel

Abstract

Immunity to human immunodeficiency virus virion-like structures or a polyprotein has been examined after DNA immunization with Rev-independent expression vectors. A Gag-Pol fusion protein stimulated cytotoxic T lymphocyte and antibody responses to Gag and Pol, while a Gag-Pol pseudoparticle did not elicit substantial Pol responses. This fusion protein may be useful for AIDS vaccines.

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Citations

Apr 11, 2003·Virus Research·Gary J Nabel
May 2, 2002·Vaccine·Gary J Nabel
May 2, 2002·Vaccine·Karuppiah MuthumaniDavid B Weiner
Mar 22, 2002·Nature Reviews. Immunology·J A BerzofskyI M Belyakov
May 11, 2002·Nature Reviews. Immunology·Harriet L Robinson
Nov 17, 2006·The Journal of Infectious Diseases·Andrew T CatanzaroUNKNOWN Vaccine Research Center 006 Study Team
Nov 17, 2006·The Journal of Infectious Diseases·Barney S GrahamUNKNOWN Vaccine Research Center 004 Study Team
Jul 10, 2004·AIDS Research and Human Retroviruses·James M SmithHarriet L Robinson
Jan 28, 2006·AIDS Research and Human Retroviruses·Kelly R Young, Ted M Ross
Dec 25, 2008·Nucleic Acids Research·Cameron P KeatingJohnson Mak
Apr 16, 2004·Clinical Microbiology Reviews·Malavika GiriDavid B Weiner
Jul 9, 2010·Journal of Virology·Sarra E KeeneAlice Telesnitsky
Nov 12, 2003·Journal of Virology·Wing-Pui KongGary J Nabel
Jun 29, 2004·Journal of Virology·Norman L LetvinGary J Nabel
Aug 29, 2003·Molecular and Cellular Biology·Andrei S ZolotukhinBarbara K Felber
Jan 8, 2011·Retrovirology·Jing MaShan Cen

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