Human intramuscular and cutaneous pain: psychophysical comparisons

Experimental Brain Research
P SvenssonK L Casey

Abstract

We used psychophysical methods to compare the central processing of nociceptive inputs from skin and muscle in ten normal humans. Both intramuscular electrical and infrared CO2 laser cutaneous stimulation showed increasing but decelerating (downward concave) stimulus-response curves and similar temporal summation characteristics. Intramuscular stimulation was rated significantly more unpleasant than cutaneous stimulation. The results are consistent with a common mode of central nociceptive processing for skin and muscle pain intensity but suggest a relatively larger activation of affective mechanisms by muscle afferents.

Citations

Nov 3, 2011·Experimental Brain Research·Line Lindhardt EgsgaardLars Arendt-Nielsen
Dec 25, 2003·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Peng Fei ChangAndrew C N Chen
Jan 1, 1997·European Journal of Pain : EJP·R J LaursenL Arendt-Nielsen
Apr 6, 2001·The Clinical Journal of Pain·T Graven-Nielsen, S Mense
Jul 8, 1999·Proceedings of the National Academy of Sciences of the United States of America·M C BushnellB Carrier
Jun 23, 2009·Journal of the Chinese Medical Association : JCMA·David M Niddam, Jen-Chuen Hsieh
Apr 11, 2001·Lasers in Surgery and Medicine·M GülsoyI Cilesiz
Mar 15, 2016·Pain Management·Shafaq SikandarAnthony H Dickenson
Dec 20, 2005·Pain·William GibsonThomas Graven-Nielsen
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Sep 26, 2006·Scandinavian Journal of Rheumatology. Supplement·T Graven-Nielsen
Jul 20, 2017·Physiological Reports·Shafaq SikandarAnthony H Dickenson

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