Human lens capsule thickness as a function of age and location along the sagittal lens perimeter

Investigative Ophthalmology & Visual Science
Rafael I BarraquerFrancisco Tresserra

Abstract

To investigate the variation in the thickness of the human lens capsule along the lens perimeter, as well as its changes with age. Altogether, 26 human donor lenses, aged 12 to 103 years, were histologically processed. Sagittal sections were stained for collagen with periodic acid-Schiff (PAS). Serial images of the lens border were taken with a photomicroscope and 25x objective. Capsular thickness was measured every 250 microm along the entire lens perimeter. All studied capsules were thicker anteriorly, continuously increasing with age from 11 to 15 microm in average at the anterior lens pole. Maximum thickness was located at the anterior midperiphery, increasing with age from 13.5 to 16 microm. In most cases, there was a local thinning at a pre-equatorial zone, recovering to approximately 7 microm at the equator. The latter value, as well as the minimal thickness at the posterior pole (mean 3.5 microm), did not change with age, whereas the average thickness at the posterior periphery decreased from 9 to 4 microm. The human lens capsule thickness is at its maximum at the anterior midperiphery, which appears to be located central to the zonular insertion. It increases with age, especially at the anterior pole, while the midperi...Continue Reading

Citations

Jul 12, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ronald A Schachar
Jun 15, 2011·Journal of Proteome Research·Maurizio RonciNicolas H Voelcker
Mar 9, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Jason L SandersUNKNOWN Health ABC Study
Sep 8, 2010·Journal of Biomechanical Engineering·Tracy A PowellVictor H Barocas
Dec 19, 2012·Human Genomics·Konstantinos Sousounis, Panagiotis A Tsonis
Jun 15, 2007·Theoretical Biology & Medical Modelling·Susann G Remington, Rita A Meyer
Jan 28, 2014·Journal of Cataract and Refractive Surgery·David J SpaltonI Michael Wormstone
Dec 19, 2012·Journal of Cataract and Refractive Surgery·Gerd U AuffarthTanja M Rabsilber
Jan 16, 2016·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Mary Ann CroftPaul L Kaufman
Feb 16, 2010·Journal of Cataract and Refractive Surgery·Michael E Snyder, Luke B Lindsell
May 29, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Kwan Soo KimChul Young Choi
Sep 9, 2008·Experimental Eye Research·Brian P Danysh, Melinda K Duncan
Sep 28, 2015·Survey of Ophthalmology·Dilraj S GrewalH Burkhard Dick
Oct 28, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Brian P DanyshMelinda K Duncan
Feb 27, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·H J Burd, G S Wilde
Apr 2, 2015·The British Journal of Ophthalmology·Mark PackerSteven Bott
May 10, 2015·Biomechanics and Modeling in Mechanobiology·H J Burd, R A Regueiro
Jul 28, 2013·Current Eye Research·Christian KastnerKlaus-Peter Schmitz
Aug 4, 2015·Journal of Ophthalmology·Mahmoud Mohamed FaroukYoshinori Mitamura
Nov 27, 2014·Computer Methods in Biomechanics and Biomedical Engineering·Xiaoyu LiuYubo Fan
Oct 25, 2016·Ophthalmology·Chaiwat TeekhasaeneeRobert Ritch
Jul 27, 2017·Vestnik oftalmologii·K S AvetisovI V Khaydukova
Oct 28, 2017·International Ophthalmology·Aikaterini I MoulakakiRobert Montés-Micó
Dec 2, 2017·Scientific Reports·Kehao WangBarbara K Pierscionek
Feb 9, 2018·Journal of Glaucoma·Chaiwat Teekhasaenee
Dec 5, 2018·Journal of Cataract and Refractive Surgery·Sheraz M DayaDavid H Mordaunt
Jul 10, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Jack PhuMichael Kalloniatis
Sep 15, 2017·Current Eye Research·Muhammed BaturTekin Yasar
Jul 19, 2012·Biomedical Optics Express·Mehdi Bahrami, Alexander V Goncharov
May 3, 2019·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Kehao WangBarbara K Pierscionek
Feb 25, 2020·Journal of the Mechanical Behavior of Biomedical Materials·K S AvetisovP S Timashev
Jan 26, 2021·Biomechanics and Modeling in Mechanobiology·Katherine R KnausSilvia S Blemker
Feb 6, 2021·Computer Methods in Biomechanics and Biomedical Engineering·S F Han, Y Yang
Mar 15, 2021·Computer Methods and Programs in Biomedicine·Shaofeng HanYang Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Investigative Ophthalmology & Visual Science
Susanne Krag, Troels T Andreassen
The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Brian P DanyshMelinda K Duncan
© 2022 Meta ULC. All rights reserved