Human microbiome: an academic update on human body site specific surveillance and its possible role

Archives of Microbiology
Elakshi DekaboruahAnil Kumar Verma

Abstract

Human body is inhabited by vast number of microorganisms which form a complex ecological community and influence the human physiology, in the aspect of both health and diseases. These microbes show a relationship with the human immune system based on coevolution and, therefore, have a tremendous potential to contribute to the metabolic function, protection against the pathogen and in providing nutrients and energy. However, of these microbes, many carry out some functions that play a crucial role in the host physiology and may even cause diseases. The introduction of new molecular technologies such as transcriptomics, metagenomics and metabolomics has contributed to the upliftment on the findings of the microbiome linked to the humans in the recent past. These rapidly developing technologies are boosting our capacity to understand about the human body-associated microbiome and its association with the human health. The highlights of this review are inclusion of how to derive microbiome data and the interaction between human and associated microbiome to provide an insight on the role played by the microbiome in biological processes of the human body as well as the development of major human diseases.

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Citations

Jan 12, 2021·Expert Review of Clinical Immunology·Larissa Koidl, Eva Untersmayr
Apr 14, 2021·ACS Infectious Diseases·Fulvio BorellaChiara Benedetto
Jul 25, 2021·Seminars in Cancer Biology·Mohd WahidRamandeep Rattan
Aug 28, 2021·Genes·Alessandro MaglioneSimona Rolla
Sep 25, 2021·Applied Microbiology and Biotechnology·Felizitas BajerskiJoerg Overmann
Oct 14, 2021·Cancer·Sylvia L CrowderHeather S L Jim
Nov 30, 2021·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Xiangqian LiuSulie L Chang
Dec 27, 2021·Journal of Applied Microbiology·Mateusz SperudaRafał Ogórek

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Methods Mentioned

BETA
single-cell sequencing
PCR

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