Human microbiome restoration and safety

International Journal of Medical Microbiology : IJMM
Eric Banan-Mwine DaliriDeog-Hwan Oh

Abstract

The human gut microbiome consists of many bacteria which are in symbiotic relationship with human beings. The gut microbial metabolism, as well as the microbial-host co-metabolism, has been found to greatly influence health and disease. Factors such as diet, antibiotic use and lifestyle have been associated with alterations in the gut microbial community and may result in several pathological conditions. For this reason, several strategies including fecal microbiota transplant and probiotic administration have been applied and proven to be feasible and effective in restoring the gut microbiota in humans. Yet, safety concerns such as potential health risks that may arise from such interventions and how these strategies are regulated need to be addressed. Also, it will be important to know if these microbiome restoration strategies can have a profound impact on health. This review provides an overview of our current knowledge of the microbiome restoration strategies and safety issues on how these strategies are regulated.

Citations

Sep 6, 2018·Nutrients·Anna PisanoDavide Bolignano
Jul 3, 2019·Nature Reviews. Microbiology·Madeleine J H van Oppen, Linda L Blackall
Sep 4, 2019·The ISME Journal·Kaitlyn OliphantEmma Allen-Vercoe
Aug 6, 2020·High-throughput·Eric Banan-Mwine DaliriDeog-Hwan Oh
Jun 27, 2019·American Journal of Primatology·Jenni FirrmanWilliam Rinaldi
May 24, 2019·Journal of Neuroinflammation·Francesco AngelucciJakub Hort
Jul 31, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Inge HuybrechtsNathalie Michels
Dec 27, 2019·International Immunopharmacology·Lucia Malaguarnera
Oct 30, 2020·Bioscience of Microbiota, Food and Health·Eric Banan-Mwine DaliriDeog-Hwan Oh
Mar 23, 2021·Frontiers in Microbiology·Eric Banan-Mwine DaliriDeog-Hwan Oh

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