Human papilloma virus and genitourinary cancers: a narrative review

Minerva urologica e nefrologica = The Italian journal of urology and nephrology
Tommaso CaiRiccardo Bartoletti

Abstract

Human papilloma virus (HPV) is the most common sexually transmitted pathogen and its potential role in the genesis of several diseases such as cervical, head and neck, anal and penile cancers, is now largely recognized. Aim of this review article was to evaluate and summarize the state of the art of HPV-related urogenital cancers, focusing on the potentially innovative methods for the diagnosis of infection that should be used to improve viral causative detection and prevent its diffusion through sexual intercourses. The initial search was carried out by using the Medline and the Google Scholar computerized databases through the selected key-words to identify the more recent literature on HPV epidemiology and its relationship with the main relevant urinary tract cancers. Studies were selected, extracted, analyzed and summarized. The PRISMA statement criteria were adopted and reported. Polymerase chain reaction assay (HPV test) represents the best option for the diagnosis of HPV infection. Difficulties for the diagnosis in male are due to the site of investigation (glans, sub coronal sulcus, scrotum, urine, sperm) and the method adopted to take the sample (brushing, tissue biopsy). Due to these reasons several studies analyzed s...Continue Reading

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Citations

Jul 1, 2020·International Journal of Molecular Sciences·Konrad BilskiJerzy Ostrowski
Feb 6, 2021·Expert Review of Clinical Immunology·Susana Otero-RomeroAngela Vidal-Jordana
Dec 22, 2020·International Journal of STD & AIDS·Marialuisa CorbedduFranco Rongioletti
Jun 23, 2020·Revista Internacional De Andrología·Bruno GraçaPedro Vendeira

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