PMID: 15389001Sep 25, 2004Paper

Human papillomavirus-32-positive extragenital Bowenoid papulosis (BP) in a HIV patient with typical genital BP localization

Sexually Transmitted Diseases
Anna Marta DegenerS Pala

Abstract

Bowenoid papulosis (BP) is characterized by multiple maculopapular lesions of the genitalia; extragenital localization is rarely found. Human papillomavirus (HPV) type 16 has been found in most cases of BP, but the other HPV genotypes associated with BP had been poorly characterized. We describe an extragenital BP with concomitant genital involvement in an HIV-positive woman. Several HPV gene-specific amplifications and sequencing were performed on DNA extracted from biopsy samples. The presence of HPV-16 DNA in anogenital and HPV-32 DNA in lip lesions was demonstrated in the absence of any other HPV type and with no coinfection. Semiquantitative polymerase chain reaction analysis revealed that HPV-16 and -32 DNA sequences are in the episomal state. This is the first report of BP associated with HPV-32 (the causative agent of a benign hyperplasia) and a rare case of BP associated with 2 HPV types in the same patient. The immune depression could have modified the normal benign progression of the extragenital lesions.

References

Dec 1, 1989·Diseases of the Colon and Rectum·R Rüdlinger, P Buchmann
May 18, 1989·Nature·S Kwok, R Higuchi
Mar 1, 1986·Journal of the American Academy of Dermatology·S ObalekG Orth
Feb 1, 1987·The Journal of Investigative Dermatology·S BeaudenonG Orth
Oct 1, 1981·The Journal of Urology·M S Peters, H O Perry
Oct 1, 1994·The British Journal of Dermatology·D J FaderT F Anderson
Jan 1, 1993·Journal of Virological Methods·M Contorni, P Leoncini
Jun 26, 1998·The British Journal of Dermatology·C DianzaniA M Degener
Aug 19, 1999·The Journal of Pathology·J M WalboomersN Muñoz
Oct 27, 1999·Journal of the American Academy of Dermatology·T M JohnsonL Lowe
Dec 3, 1999·The British Journal of Dermatology·S Jablonska, S Majewski
Oct 3, 2002·Virology·Sandra CaldeiraMassimo Tommasino
Jan 15, 2003·Clinical Microbiology Reviews·Eileen M Burd

❮ Previous
Next ❯

Citations

May 21, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·F FalakiN Pazooki
Jan 7, 2011·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Wolfgang HartschuhAlex Furtwängler
Apr 30, 2017·Journal of Lower Genital Tract Disease·Stephen M SmithWei Chen
Aug 8, 2007·The Australasian Journal of Dermatology·Asoka HeratRichard Hillman
Oct 1, 2019·Journal of Cutaneous Pathology·Jean C B FerreiraElismauro F Mendonça
Feb 24, 2011·International Journal of Dermatology·Maria R González-LosaNixma Eljure-Lopez
Feb 25, 2021·BioMed Research International·Luca FiorilloMarco Cicciù

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bowen's Disease

Bowen's disease is thought of as an easily-treatable early stage of skin cancer, characterized by red, scaly patches on the skin. Discover the latest research on Bowen's disease here.