Human papillomavirus and extragenital in situ carcinoma

Dermatology : International Journal for Clinical and Investigative Dermatology
G QuéreuxB Dreno

Abstract

The relation between human papillomavirus (HPV) and extragenital Bowen's disease (BD) is controversial. This study used in situ hybridisation to evaluate the rate of HPV in extragenital cutaneous BD and investigated possible relations with immune status and exposure of skin to light. HPV DNA was detected in 58% of 69 samples from 50 patients. The percentage of HPV detection was not significantly higher in exposed (55%) than unexposed areas (65%), and no difference in HPV rate was found between immunosuppressed and immunocompetent patients. Thus, this study confirms the high rate of HPV detection in extragenital cutaneous BD and suggests that there is no apparent relation concerning exposed areas and immune status.

Citations

Oct 27, 2007·Actas dermo-sifiliográficas·R Corbalán-VélezF J Carapeto
Aug 30, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Bishr AldabaghSarah T Arron
Feb 25, 2014·Clinics in Dermatology·Suzana Ljubojevic, Mihael Skerlev
Apr 20, 2011·Actas dermo-sifiliográficas·R Corbalán-VélezJ M López-Lozano
Jan 4, 2007·The British Journal of Dermatology·N H CoxUNKNOWN Therapy Guidelines and Audit Subcommittee, British Association of Dermatologists
May 29, 2012·The British Journal of Dermatology·A ShimizuO Ishikawa
Nov 13, 2014·The Journal of Dermatology·Chao-Kai HsuJulia Yu-Yun Lee

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