Human papillomavirus DNA in oral mucosal lesions

The Journal of Infectious Diseases
Lucia GiovannelliPietro Ammatuna

Abstract

This study determined the presence of human papillomavirus (HPV) DNA in oral mucosa cells from 121 patients with different types of oral mucosal lesions (13 squamous cell carcinomas, 59 potentially malignant lesions, 49 benign erosive ulcerative lesions) and from 90 control subjects. HPV DNA was detected by nested polymerase chain reaction, and genotype was determined by DNA sequencing. HPV prevalence was 61.5% in carcinomas, 27.1% in potentially malignant lesions, 26.5% in erosive ulcerative lesions, and 5.5% in control subjects. The risk of malignant or potentially malignant lesions was associated with HPV and was statistically significant. HPV-18 was found in 86.5% of HPV-positive lesions but was not associated with a particular type of lesion and was found in 80% of the HPV-positive control subjects. HPV infection was related to older age but not to sex, smoking, or alcohol use; the presence of lesions in the oral cavity increased the risk of HPV infection.

Citations

Mar 26, 2004·Cancer Genetics and Cytogenetics·Sylvia Sanches CortezziPaula Rahal
May 28, 2004·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Torsten W RemmerbachUwe Gerd Liebert
Jun 3, 2004·Oral Oncology·Lorenzo Lo MuzioMatteo D'Angelo
Oct 29, 2003·Cancer Letters·Paramee ThongsuksaiWanna Sudhikaran
Jun 4, 2010·The Journal of Laryngology and Otology·C B HeffernanC Timon
Mar 18, 2004·Journal of the National Cancer Institute·Elaine M SmithLubomir P Turek
Dec 22, 2004·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Giuseppina CampisiPietro Ammatuna
Nov 10, 2006·Journal of Clinical Microbiology·Lucia GiovannelliPietro Ammatuna
Nov 8, 2005·Journal of Clinical Microbiology·Gypsyamber D'SouzaMaura Gillison
May 10, 2005·Postgraduate Medical Journal·S J Genuis, S K Genuis
Nov 3, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Daniel C BeachlerGypsyamber D'Souza
Dec 7, 2010·Infectious Agents and Cancer·Luis O Sánchez-VargasAlejandro Martinez-Martinez
Mar 1, 2011·Infectious Agents and Cancer·Nadia LaantriMeriem Khyatti
Feb 27, 2008·The Angle Orthodontist·Tatiana Siqueira GonçalvesLuciane Macedo de Menezes
Sep 1, 2005·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Leena-Maija AaltonenAnnamari Ranki
Sep 27, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A PierangeliA Polimeni
Sep 17, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Patrizia MorbiniMarco Benazzo
Aug 24, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Maria CorrentiHelen Rivera
Jan 7, 2009·Auris, Nasus, Larynx·Márcio Campos OliveiraAntonio de Lisboa Lopes Costa
Jan 1, 2008·Archives of Medical Research·Gabriela Anaya-SaavedraAlejandro García-Carrancá
Nov 6, 2007·American Journal of Otolaryngology·Rosilene Calazans SoaresLeão P Pinto
Dec 22, 2006·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Koichi KoyamaAkio Tanaka
Feb 5, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·W A DelgadoJ E León
Jan 21, 2009·Periodontology 2000·Jørgen Slots
Jan 21, 2009·Periodontology 2000·Matti Sällberg
Apr 28, 2011·Cancer·Kazuyoshi ShigeharaMikio Namiki
Feb 24, 2011·International Journal of Dermatology·Maria R González-LosaNixma Eljure-Lopez
Jul 19, 2011·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M MigaldiA Sgambato
Oct 26, 2010·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Raquel dos Santos PinheiroGloria Fernanda Castro
Nov 18, 2014·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Davide B PuglieseLaura D Locati
Apr 24, 2013·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Kazuyoshi ShigeharaMikio Namiki
Mar 9, 2005·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·John Cason, Christine A Mant
Mar 9, 2005·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Stina Syrjänen
Jun 15, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Giovanni LodiKobkan Thongprasom
Dec 3, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Lucio MontebugnoliMaria Pia Foschini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.