PMID: 9417149Jan 17, 1998Paper

Human papillomavirus screening in pediatric victims of sexual abuse

Pediatrics
E SiegfriedJ Monteleone

Abstract

To evaluate for the presence of subclinical human papillomavirus (HPV) in cases of suspected sexual abuse in children. Prospective data collection via interviews, physical examination, colposcopic examination, and tissue sampling by a surface swab technique. A total of 40 pediatric patients ranging in age from 1 to 16 years who were referred to the Special Assessment and Management Clinic at Cardinal Glennon Children's Hospital, St Louis, MO, for probable or confirmed sexual abuse. In addition to colposcopic examination for physical signs of abuse, the patients were screened for evidence of sexually transmitted diseases, including syphilis, gonorrhea, and Chlamydia. At that time, surveillance sampling of the throat, vaginal introitus, and/or rectum by a simple, rapid surface swab technique was performed to detect the presence of HPV. Template DNA was extracted from cotton swabs and analyzed using polymerase chain reaction analysis. Human beta-globin sequences were detected in 58 (83%) of 70 specimens obtained from 40 patients, indicating successful processing had occurred. Using a consensus L1 primer-probe set capable of detecting multiple HPV genotypes, 2 (3%) of 58 samples from 2 (5%) of 40 patients were positive for HPV 16. ...Continue Reading

Citations

Jun 30, 2004·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Gail Hornor
Apr 15, 2010·Journal of Child Sexual Abuse·Selda BülbülTutku Soyer
Dec 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Margaret R Hammerschlag
Nov 30, 2006·The Pediatric Infectious Disease Journal·Ioannis N MammasDemetrios A Spandidos
Apr 1, 2005·Current Opinion in Pediatrics·Mark V Sapp, Andrea M Vandeven
Jun 20, 2006·Pediatric Dermatology·Gayle Fischer
Dec 25, 2010·Pediatric Dermatology·Mukai ChenJiande Han
Jul 9, 2010·Clinical Microbiology Reviews·Margaret R Hammerschlag, Christina D Guillén
Jun 24, 2009·Virology Journal·Renato L RombaldiKamille P Losquiavo
Mar 9, 2006·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Gail Hornor
Oct 8, 2005·Seminars in Pediatric Infectious Diseases·Sara H Sinal, Charles R Woods
Apr 20, 2005·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Jessica A KahnRobert D Burk
Mar 10, 2009·American Journal of Obstetrics and Gynecology·Daniela DoerflerElmar A Joura
May 17, 2002·American Journal of Obstetrics and Gynecology·Felipe R LorenzatoGeorge Terry

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