Human Papillomavirus Vaccine Introduction in South Africa: Implementation Lessons From an Evaluation of the National School-Based Vaccination Campaign

Global Health, Science and Practice
Sinead Delany-MoretlweHelen Rees

Abstract

In April 2014, a national school-based human papillomavirus (HPV) vaccination program was rolled out in South Africa, targeting Grade 4 girls aged ≥9 years. A bivalent HPV vaccine with a 2-dose (6 months apart) schedule was used. At the request of the National Department of Health (NDoH), we conducted an external assessment of the first-dose phase of the vaccination program to evaluate program coverage and vaccine safety and identify factors that influenced implementation. We based our cross-sectional and mixed-methods approach on a process evaluation framework, which included a review of key planning and implementation documents and monitoring data; observation at vaccination sites; key informant interviews (N=34); and an assessment of media coverage and content related to the campaign.Findings: There was overall success in key measures of coverage and safety. Over 350,000 Grade 4 girls were vaccinated in more than 16,000 public schools across South Africa, which translated to 94.6% of schools reached and 86.6% of age-eligible learners vaccinated. No major adverse events following immunization were detected. We attributed the campaign's successes to careful planning and coordination and strong leadership from the NDoH. The pri...Continue Reading

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Citations

Sep 27, 2019·Cancer·Allison L FichtB Ryan Phelps
Apr 15, 2019·International Journal of Public Health·Christian SelingerAnna Bershteyn
Apr 16, 2021·Current Opinion in Immunology·Ntombenle NgcoboEdison Mavundza
Jun 25, 2021·International Journal of Cancer. Journal International Du Cancer·Cari van SchalkwykLeigh F Johnson
Jul 13, 2021·Expert Review of Vaccines·Sara CooperCharles Shey Wiysonge
Jun 14, 2021·Clinical Obstetrics and Gynecology·Emma R Allanson, Kathleen M Schmeler

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