Human PCDD/PCDF levels near a pentachlorophenol contamination site in Tainan, Taiwan

Chemosphere
Ching-Chang LeePao-Chi Liao

Abstract

A pentachlorophenol (PCP) manufacturing plant in southern Taiwan discontinued production in 1989. The site of the abandoned plant was heavily contaminated by PCDD/PCDFs, impurities formed in the PCP production process. Serum samples collected from 27 residents living near the deserted plant were evaluated to determine whether this contamination had associated serum levels of PCDD/PCDFs in local residents. The average level of 17 tested congeners ranged from 556 to 5240 pg/g lipid (mean, 1670 pg/g lipid). The corresponding 2,3,7,8-TCDD toxicity equivalent quotient values calculated by international toxicity equivalent factors (I-TEFs) and those recommended by WHO (WHO-TEFs) were 47.2 pg I-TEQ/g lipid and 53.4 pg WHO-TEQ/g lipid, respectively. Levels in other parts of Taiwan typically range from 15 to 20 pg WHO-TEQ/g lipid; therefore, it is likely that the heavily contaminated plant site caused these unusually high serum levels. The average PCDD/PCDF levels of 29 fish-tissue and nine soil samples collected from the sea reservoir surrounding the abandoned PCP plant were also abnormally high: 8630 pg/g lipid (985 pg WHO-TEQ/g lipid) and 606000 pg/g-sample (922 pg WHO-TEQ/g-sample), respectively. Factor analysis indicated that the c...Continue Reading

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Citations

Dec 8, 2015·Environmental Monitoring and Assessment·Pei-Yu LiaoWen-Yao Liu
Mar 1, 2012·Environment International·Dario ConsonniPier Alberto Bertazzi
Dec 15, 2015·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Hwang-Jen ChangYi-Ju Wu
Oct 16, 2007·The Science of the Total Environment·Quan-Ying CaiQiao-Yun Zeng
Sep 21, 2013·Chemico-biological Interactions·Hsiu-Min ChenYing-Jan Wang
May 7, 2010·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Hwang J ChangYi C Lai
Oct 30, 2020·Journal of Hazardous Materials·Bao-Anh Thi NguyenChieh-Chen Huang
Jun 5, 2010·Journal of Agricultural and Food Chemistry·Jing-Fang HsuPao-Chi Liao

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