Human pegivirus in brain tissue of a patient with encephalitis

Diagnostic Microbiology and Infectious Disease
Renee TuddenhamJames M Branley

Abstract

We describe a case of meningoencephalitis in which meta-transcriptomic (RNA) sequencing detected human pegivirus (HPgV) in brain tissue, cerebrospinal fluid, and serum in the absence of other pathogens. This is the first detection of HPgV in antemortem brain tissue, although it is uncertain whether HPgV is responsible for the observed encephalitis.

Citations

Nov 27, 2020·Virus Evolution·Ashleigh F PorterEdward C Holmes
Aug 21, 2021·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Marianne GraningerElisabeth Puchhammer-Stöckl

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