Human platelet and fluorochemical interaction

Journal of Biomedical Materials Research
J J KmetzoH W Wallace

Abstract

Since the fluorochemicals have become of interest for the development of artificial red blood cells, oxygenators, liquid breathing, and as a radiographic contrast medium, their interaction with biological substances is of importance. Fresh human platelets were placed in contact with four different fluorochemicals for a period of 50 min. The platelet function as measured by aggregation was determined before and after fluorochemical contact. Appropriate controls were also evaluated. No significant differences were found between the aggregation of platelets contacted with fluorochemicals and the aggregation of platelets from the same donor unexposed to fluorochemicals.

References

Jun 29, 1971·European Journal of Biochemistry·V Ullrich, H Diehl
Nov 1, 1974·Microvascular Research·L C ClarkS Kaplan
Nov 15, 1973·The New England Journal of Medicine·R P Geyer
Oct 1, 1965·Archives of Surgery·S HowlettD C Sabiston
Nov 4, 1967·Nature·H A Sloviter, T Kamimoto
Aug 1, 1963·The Journal of Physiology·G V BORN, M J CROSS

Citations

Jan 1, 1988·Journal of Biomedical Materials Research·V V TulianiB D Sierra
Jul 1, 1985·American Journal of Hematology·C A ReindorfO Castro

Related Concepts

Hemocompatible Materials
Zyderm
Medihaler-Epi
Fluorides
Telomer Fluorocarbons
Platelet Aggregation

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