PMID: 7204562Mar 1, 1981

Human platelet stimulation by acetyl glyceryl ether phosphorylcholine

The Journal of Clinical Investigation
L M McManusR N Pinckard

Abstract

Acetyl glyceryl ether phosphorylcholine (AGEPC) induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma. ADP scavengers or indomethacin prevented irreversible platelet aggregation responses induced by 0.2 microM AGEPC but had no effect upon platelet secretion; prostacyclin inhibited AGEPC-induced aggregation and secretion. EDTA or EGTA inhibited AGEPC-induced aggregation but had no effect on platelet secretion.

Citations

Jun 1, 1983·Inflammation·C M Suquet, R W Leid
Feb 8, 2013·Current Heart Failure Reports·Paraskevi DetopoulouSmaragdi Antonopoulou
Sep 21, 2013·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·C DoutremepuichFrancisco X Eizayaga
Oct 15, 1989·Biochemical Pharmacology·C L KeralyJ Benveniste
Apr 9, 1986·European Journal of Pharmacology·W HsuehW J Houlihan
Sep 1, 1989·European Journal of Pharmacology·D F WoodwardL S Williams
Jan 1, 1988·The International Journal of Biochemistry·Constantinos A DemopoulosR Stathopoulou-Sparou
Apr 25, 1983·Life Sciences·Z TerashitaK Nishikawa
Jan 1, 1988·Toxicon : Official Journal of the International Society on Toxinology·R S ReesL E King
Aug 1, 1984·Veterinary Immunology and Immunopathology·H D LiggittL Huston
Jan 1, 1986·Prostaglandins, Leukotrienes, and Medicine·J MehtaW W Nichols
Sep 1, 1992·Comparative Biochemistry and Physiology. Comparative Physiology·M A PackhamR L Kinlough-Rathbone
Apr 13, 1982·Biochimica Et Biophysica Acta·G H RaoJ G White
Apr 23, 1997·European Journal of Pharmacology·D H AlbertG W Carter
Dec 13, 2000·Thrombosis Research·O AguejoufC Doutremepuich
Jun 11, 1998·Thrombosis Research·O AguejoufC Doutremepuich
Jun 4, 1981·The New England Journal of Medicine·K A KnauerJ E Fish
Feb 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M M Billah, E G Lapetina
May 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·S R Hanson, L A Harker
May 1, 1991·Scandinavian Journal of Immunology·J R GeffnerM A Isturiz
Aug 1, 1987·Clinical and Experimental Pharmacology & Physiology·R R TaylorL J Beilin
Aug 1, 1992·Clinical and Experimental Pharmacology & Physiology·N L Misso, P J Thompson
Dec 1, 1985·The Journal of Clinical Investigation·G A ZimmermanS M Prescott
Jun 1, 1986·The Journal of Clinical Investigation·F BussolinoE Dejana
Dec 1, 1986·The Journal of Clinical Investigation·A J WardlawA B Kay
Mar 1, 1994·Agents and Actions·R LouisM F Radermecker
Aug 1, 1988·Agents and Actions·F Q CunhaS H Ferreira
Feb 29, 1988·Clinica Chimica Acta; International Journal of Clinical Chemistry·N TatsumiT Kyougoku
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·M C CabotF Snyder
Sep 1, 1984·The Journal of Allergy and Clinical Immunology·S I Wasserman, M H Ginsberg
Oct 1, 1992·Journal of Comparative Pathology·P A Gentry
Oct 1, 1996·Prostaglandins, Leukotrienes, and Essential Fatty Acids·K Shindo, M Fukumura
Aug 15, 1986·Thrombosis Research·L J KüsterJ C Frölich
Jan 15, 1989·Thrombosis Research·D O BeaumontC W Slattery
Oct 21, 2005·Diabetes Research and Clinical Practice·Haralabos C KarantonisConstantinos A Demopoulos
Mar 16, 1981·Biochemical and Biophysical Research Communications·D J HanahanR N Pinckard
Feb 1, 1997·Japanese Circulation Journal·T TamuraM Inada
Nov 20, 2012·Fitoterapia·Preeti SinghVipin Kumar Garg
Feb 25, 2009·International Journal of Cardiology·Dan ZhaoBao-Feng Yang
Feb 15, 1990·Thrombosis Research·D G MoonJ W Fenton
Apr 30, 1984·Biochemical and Biophysical Research Communications·G C White
May 1, 1988·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·R E WhatleyS M Prescott
Feb 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S B MustafaM S Olson
Jul 1, 1987·Allergy·A J Wardlaw, A B Kay
Feb 1, 1987·European Journal of Clinical Investigation·C CarameloL Hernando
May 1, 1984·American Journal of Hematology·C J Pelczar-WissnerI I Sussman
Nov 1, 1990·Acta Oto-laryngologica·T Ganbo, K Hisamatsu
Jan 1, 1988·Critical Reviews in Clinical Laboratory Sciences·J A Shafer, D L Higgins
Jan 1, 1983·Critical Reviews in Clinical Laboratory Sciences·M L Tiffany
Nov 1, 1984·British Journal of Pharmacology·F Fouque, B B Vargaftig
Jun 27, 2020·Frontiers in Microbiology·Muhammad Suleman RiazAnsar Ahmed Pathan
Jun 1, 1990·Asia-Oceania Journal of Obstetrics and Gynaecology·M AndoS Matsuura

Related Concepts

Blood Coagulation Factor
Blood Platelets
Dose-Response Relationship, Drug
Lysophosphatidylcholines
Platelet Activating Factor
Platelet Aggregation
Platelet Factor 4
Hydroxytryptamine

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.