PMID: 2114367DOI: 10.1128/iai.58.7.2383-2385.1990Jul 1, 1990Paper
Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms.
Infection and Immunity
E T JensenN Høiby
Abstract
The interaction of human neutrophils with Pseudomonas aeruginosa biofilms was examined by using a chemiluminescence assay. The biofilms induced an oxidative burst response by polymorphonuclear leukocytes which was slow and only 25% of the response to planktonic bacteria. The reduced response to P. aeruginosa biofilms could play a role in the persistence of bacteria in chronic infections.
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