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Human primary endothelial cells are impaired in nucleotide excision repair and sensitive to benzo[a]pyrene compared with smooth muscle cells and pericytes

Scientific Reports

Sep 24, 2019

Joana Melanie KressBernd Kaina

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Abstract

The endothelium represents the inner cell layer of blood vessels and is supported by smooth muscle cells and pericytes, which form the vessel structure. The endothelium is involved in the pathogenesis of many diseases, including the development of atherosclerosis. Due to direct blood co...read more

Mentioned in this Paper

Atherosclerosis
Base Sequence
Benzo(a)pyrene
Blood
Blood Vessel
Cell Aging
DNA
DNA Repair
Endothelium
Environment
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Human primary endothelial cells are impaired in nucleotide excision repair and sensitive to benzo[a]pyrene compared with smooth muscle cells and pericytes

Scientific Reports

Sep 24, 2019

Joana Melanie KressBernd Kaina

PMID: 31551436

DOI: 10.1038/s41598-019-49953-w

Abstract

The endothelium represents the inner cell layer of blood vessels and is supported by smooth muscle cells and pericytes, which form the vessel structure. The endothelium is involved in the pathogenesis of many diseases, including the development of atherosclerosis. Due to direct blood co...read more

Mentioned in this Paper

Atherosclerosis
Base Sequence
Benzo(a)pyrene
Blood
Blood Vessel

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