PMID: 7279800Jan 1, 1980

Human prostatic adenocarcinoma: some characteristics of a serially transplantable line in nude mice (PC 82)

The Prostate
W HoehnP Hermanek


Transplantation of tissue from a cribriform human prostatic carcinoma resulted in a serially transplantable tumor line in nude mice, PC 82. During 2 1/2 years the tumor has not changed its histological appearance and remained a moderately differentiated adenocarcinoma. The cells contain large amounts of prostatic acid phosphatase. It has a slow rate of growth and regresses after castration and estrogen treatment. This preliminary information suggests that the PC 82 tumor line may be suitable model for hormone-dependent human prostatic cancer.


Dec 5, 2000·The Prostate·D R ChesireW B Isaacs
Oct 18, 2002·International Journal of Cancer. Journal International Du Cancer·Paul C M S VerhagenJ Trapman
Nov 1, 1988·Cancer Metastasis Reviews·J MatternM Volm
Jan 1, 1984·Cancer Metastasis Reviews·F E Sharkey, J Fogh
Jul 10, 2010·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Ketao JinGuangliang Li
Aug 1, 1988·Cancer Genetics and Cytogenetics·J J KönigF H Schröder
Nov 25, 1987·Biochimica Et Biophysica Acta·J L Ware
Dec 20, 1990·The Journal of Steroid Biochemistry and Molecular Biology·J TrapmanA O Brinkmann
Dec 20, 1990·The Journal of Steroid Biochemistry and Molecular Biology·Wytske van WeerdenF H Schröder
Jul 1, 1996·Urologic Oncology·Wytske van Weerden, G J van Steenbrugge
Apr 7, 2010·Asian Journal of Andrology·Lluis A Lopez-Barcons
May 13, 2014·Advanced Drug Delivery Reviews·Stuart J EllemGail P Risbridger
Oct 31, 2009·Journal of Cellular and Molecular Medicine·Lluis-A Lopez-Barcons
Jan 12, 2005·The Journal of Urology·R E Sobel, M D Sadar
Jul 1, 1987·European Journal of Cancer & Clinical Oncology·M R SchneiderF Sinowatz
Apr 1, 1992·Human Pathology·A A Sandberg
Nov 15, 1989·International Journal of Cancer. Journal International Du Cancer·A R BrothmanD J Merchant
Sep 15, 1983·International Journal of Cancer. Journal International Du Cancer·S A MetcalfeB T Hill


Jun 1, 1976·Journal of the National Cancer Institute·Y ShimosatoT Nomura
Mar 1, 1978·Journal of the National Cancer Institute·S D GrahamD F Paulson
Mar 15, 1978·International Journal of Cancer. Journal International Du Cancer·K R StoneD F Paulson
Jan 9, 1976·Science·W A Nelson-Rees, R R Flandermeyer
Dec 1, 1973·Journal of Virology·Y M CentifantoS L Deardourff

Related Concepts

Prostatic Neoplasms
Acid Phosphatase
Estradiol, (16 alpha,17 beta)-Isomer
House mice
Prostate Carcinoma
ACPP gene
Cell Differentiation Process
Cell Division Phases
Electron Microscopy

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.