PMID: 6159368Aug 1, 1980Paper

Human pulmonary macrophages: the relationship of smoking to the presence of sea blue granules and surfactant turnover

Journal of Clinical Pathology
P N Plowman, R J Flemans

Abstract

Human pulmonary macrophages from heavy smokers usually (17/21 cases) contain sea blue inclusion material in the cytoplasm. In non-smokers, sea blue material is rarely evident (1/21 cases). The sea blue material observed has the same properties as sea blue material identified in other conditions (viz, Sudan black and PAS positivity and autofluorescence). Evidence is presented which suggests that pulmonary macrophages from smokers contain extra surfactant and that it is this phospholipid complex that accounts for the sea blue reaction observed.

References

Oct 1, 1976·The Journal of Experimental Medicine·B A Nichols
Oct 1, 1977·Journal of Clinical Pathology·G F BurnsF G Hayhoe
May 1, 1977·Scandinavian Journal of Haematology·K E HiggyF G Hayhoe
Jul 1, 1976·Journal of Clinical Pathology·A C ParkerD H Boyd
Dec 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·C Y LiK W Lam
Jul 11, 1970·Lancet·B JonesH Thompson
Jan 1, 1970·The New England Journal of Medicine·M N SilversteinE J Ahern
Feb 3, 1972·The New England Journal of Medicine·T N Finley, A J Ladman
Feb 3, 1972·The New England Journal of Medicine·J A Clements

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