Jan 1, 1976

Human semen ribonuclease. Location, properties and inhibition by sodium dodecyl sulfate, zinc sulfate and EDTA

International Journal of Fertility
A MujicaH Hernandez-Montes

Abstract

Optimal conditions were established for RNase activity measurement. The enzyme was measured in human seminal plasma as well as in spermatozoa. Results suggest that sperm enzyme may come from seminal plasma contamination and that RNase may be used as a marker enzyme for seminal plasma contamination. Sodium dodecylsulfate, a reagent utilized to produce the solubilization of the spermatozoa, produced a very strong inhibition of the RNase at low concentrations (530 muM). Zinc sulfate and EDTA also produced inhibition of the RNase activity. Such inhibition may be very useful in future studies of RNA metabolism in human spermatozoa.

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Mentioned in this Paper

RNase Activity
Seminal Fluid
Mercury
Zinc Sulfate
Sperm Cell
Spermatozoa Cell Count
Sputolysin
Semen
RNA Metabolism
Alkaline Ribonuclease

About this Paper

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