Human stomach alcohol dehydrogenase: isoenzyme composition and catalytic properties

Alcoholism, Clinical and Experimental Research
J Hempel, R Pietruszko

Abstract

Two isoenzymes of alcohol dehydrogenase have been purified from human stomach and characterized with regard to electrophoretic mobility and kinetic properties with ethanol, hexanol, and acetaldehyde. Both undergo a time-dependent formation of multiple electrophoretic bands; the total amount of alcohol dehydrogenase activity in an average human stomach is only about 0.2% of that of the liver.

References

Nov 1, 1975·Archives of Biochemistry and Biophysics·A I CederbaumE Rubin
Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·T K LiB L Vallee
Jan 10, 1977·Biochemical and Biophysical Research Communications·W F Borson, T K Li
Mar 3, 1975·Biochemical and Biophysical Research Communications·T K Li, L J Magnes
Nov 1, 1972·Archives of Biochemistry and Biophysics·R PietruszkoC De Zalenski
Feb 1, 1971·Annals of Human Genetics·M SmithH Harris
Apr 1, 1969·Archives of Biochemistry and Biophysics·R Pietruszko, H Theorell
Aug 1, 1967·Archives of Biochemistry and Biophysics·N Mourad, C L Woronick

Citations

Dec 1, 1995·Digestive Diseases and Sciences·S C BatraC S Lieber
Jan 1, 1990·Pharmacology & Therapeutics·C S Lieber
Dec 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·T B BeisswengerB L Vallee
Jun 1, 1992·The Journal of Clinical Investigation·T SmithM D Levitt
Nov 1, 1981·Toxicology and Applied Pharmacology·A EstivalA Ribet
Mar 1, 1995·Gastroenterology·S A Mirmiran-YazdyC S Lieber
Feb 1, 1984·Biochemical Medicine·M M SaleemZ Al-Habbal
Aug 1, 1993·Alcoholism, Clinical and Experimental Research·C L StoneT K Li
Dec 1, 1990·Alcoholism, Clinical and Experimental Research·R Hernández-MuñozC S Lieber
Sep 1, 1984·The Proceedings of the Nutrition Society·M D Holdsworth, L Davies
Sep 1, 1984·The Proceedings of the Nutrition Society·R C Denney, R Johnson
Nov 1, 1981·Psychological Medicine·J McCartney, P J O'Donnell
Feb 1, 1995·Alimentary Pharmacology & Therapeutics·A S BrownO F James
Apr 8, 1998·Nutrition Reviews·H K Seitz, C M Oneta

Related Concepts

Alcohol Oxidoreductases
Catalysis
Structure of Pyloric Gland
Structure of Intestinal Gland
Alloenzymes
In Vitro [Publication Type]

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