Abstract
The U.S. Environmental Protection Agency assisted the North Carolina Department of Health and Human Services in conducting a study to investigate the potential for an association between fish kills in the North Carolina estuary system and the risk for persistent health effects. Impetus for the study was recent evidence suggesting that estuarine dinoflagellates, including members of the toxic Pfiesteria complex (TPC), P. piscicida and P. schumwayae, may release a toxin(s) that kills fish and adversely affects human health. This report describes one component of the study in which visual system function was assessed. Participants working primarily in estuaries inhabited by TPC or in off-shore waters thought not to contain TPC were studied. The potentially exposed estuary (n = 22) and unexposed offshore (n = 20) workers were matched for age, gender, and education. Visual acuity did not differ significantly between the cohorts, but visual contrast sensitivity (VCS), an indicator of visual pattern-detection ability for stimuli of various sizes, was significantly reduced by about 30% in the estuary relative to the offshore cohort. A further analysis that excluded participants having a history possibly predictive of neuropsychological...Continue Reading
Citations
Feb 5, 2004·Current Treatment Options in Neurology·Michael R. Watters, Elijah W. Stommel
Jun 12, 2003·Neurotoxicology and Teratology·Edward D LevinJohn S Ramsdell
Jun 18, 2002·Microbes and Infection·Marian SwinkerDonald Schmechel
Apr 23, 2003·Microbes and Infection·H Kenneth Hudnell, Ritchie C Shoemaker
May 17, 2005·Journal of the International Neuropsychological Society : JINS·Melissa A Friedman, Bonnie E Levin
Oct 26, 2001·Environmental Health Perspectives·C RubinH S Rogers
Nov 1, 2001·Environmental Health Perspectives·J SametT Smayda
Oct 26, 2001·Environmental Health Perspectives·R C Shoemaker
Apr 14, 2007·Environmental Health Perspectives·Ritchie C Shoemaker, Wayne Lawson
Apr 29, 2006·Advances in Therapy·Ritchie C ShoemakerUNKNOWN COL40155 Study Team
May 1, 2005·Environmental Toxicology and Pharmacology·Andrew M Geller
Oct 3, 2006·Neurotoxicology and Teratology·Ritchie C Shoemaker, Dennis E House
Aug 17, 2005·Neurotoxicology and Teratology·H Kenneth Hudnell
Jul 16, 2002·Environmental Health Perspectives·Judith S SchreiberJean C Parker
Jun 13, 2001·Environmental Health Perspectives·R C Shoemaker, H K Hudnell
Oct 26, 2001·Environmental Health Perspectives·C L MoeD J Weber
Jan 8, 2003·Environmental Health Perspectives·Ainsley H ChalmersAnthony H Winefield
Jan 8, 2003·Environmental Health Perspectives·Marian Swinker
Mar 8, 2002·Environmental Health Perspectives·Marian Swinker, William A Burke
Feb 1, 2005·Neurotoxicology and Teratology·Ritchie C Shoemaker, Dennis E House