PMID: 9549101Jan 1, 1997Paper

Humoral immune response to Malassezia furfur in patients with pityriasis versicolor and seborrheic dermatitis

Mycopathologia
V SilvaZ P de Camargo

Abstract

Humoral immune responses against exoantigen components of oval, elliptic and round yeast forms of Malassezia furfur were analysed by ELISA and Western blotting assays, using sera from patients with pityriasis versicolor (PV), seborrheic dermatitis (SD) and healthy adults (HA), as control. Sera from patients with SD showed IgG anti-oval M. furfur titers ranging from 1/400 to 1/6400 showing geometric mean (GM) of 1/1472, higher than those obtained with sera from patients with PV (1/200 to 1/6400, GM = 1/1239). Both patient groups showed mean titres statistically superior (P < 0.05) than those obtained form HA (GM = 1/229). Similar data were also obtained with the elliptic and round antigens. However, the anti-oval IgG mean titers from patients' sera were much higher than those obtained with elliptic or round antigenic components (p < 0.05) Anti-M furfur IgM titers obtained from patient's sera with PV against all three exoantigens were statistically superior (p < 0.05) than HA group. Patients with SD showed IgM titers statistically superior (p < 0.05) only to oval yeasts of M. furfur. The IgA mean titers from patients' groups against the different morphological antigens were shown be slightly higher than those HA group. By Western...Continue Reading

Citations

Apr 20, 2002·Current Opinion in Infectious Diseases·Vicente Crespo Erchiga, Vicente Delgado Florencio
Jan 10, 2002·Clinical Microbiology Reviews·H Ruth Ashbee, E Glyn V Evans
Dec 22, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M Tengvall LinderC Wahlgren
Jul 20, 2007·Clinical and Vaccine Immunology : CVI·Rodrigo Almeida-PaesRosely Maria Zancopé-Oliveira
Oct 15, 2009·Phytotherapy Research : PTR·Rosana FilipClaudia Anesini
Feb 13, 2021·Frontiers in Cellular and Infection Microbiology·Shree Harsha Vijaya ChandraJohn E Common

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