journal cover

Huntington's disease: from molecular pathogenesis to clinical treatment

Lancet Neurology

Dec 18, 2010

Christopher A Ross, Sarah J Tabrizi

Abstract

Huntington's disease is a progressive, fatal, neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene, which encodes an abnormally long polyglutamine repeat in the huntingtin protein. Huntington's disease has served as a model for the study of other more commo...read more

Mentioned in this Paper

Histone Deacetylase
MTOR gene
GRIK2 gene
HAP1 gene
HTT gene
PPARGC1A gene
TCERG1 gene
RASD2 gene
Huntington Disease
Kainate
2
1
1410
1
Paper Details
References
  • References38
  • Citations354
  • References38
  • Citations354
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Huntington's disease: from molecular pathogenesis to clinical treatment

Lancet Neurology

Dec 18, 2010

Christopher A Ross, Sarah J Tabrizi

PMID: 21163446

DOI: 10.1016/s1474-4422(10)70245-3

Abstract

Huntington's disease is a progressive, fatal, neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene, which encodes an abnormally long polyglutamine repeat in the huntingtin protein. Huntington's disease has served as a model for the study of other more commo...read more

Mentioned in this Paper

Histone Deacetylase
MTOR gene
GRIK2 gene
HAP1 gene
HTT gene
PPARGC1A gene
TCERG1 gene
RASD2 gene
Huntington Disease
Kainate
2
1
1410
1

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References38
  • Citations354
  • References38
  • Citations354
12345...
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