"Hurdles on the path to 90-90-90 and beyond": Qualitative analysis of barriers to engagement in HIV care among individuals in rural East Africa in the context of test-and-treat

PloS One
James AyiekoCarol S Camlin

Abstract

Despite substantial progress, gaps in the HIV care cascade remain large: globally, while about 36.7 million people were living with HIV in 2015, 11.9 million of these individuals did not know their HIV status, 12.7 million were in need of antiretroviral therapy (ART) and 13.0 million were not virally suppressed. We sought to deepen understanding of the barriers to care engagement at three critical steps of the care cascade proposed to make greatest impact for attaining the UNAIDS 90-90-90 targets aimed at shutting down the HIV epidemic. Analyses were conducted among HIV-infected adults in rural East Africa. Qualitative data were collected using in-depth interviews among 63 individuals participating in an ongoing test-and treat trial (NCT01864683) in its baseline year (July 2013-June 2014). Audio recordings were transcribed, translated into English, and coded using Atlas.ti software. Data were analyzed using a thematic framework for explaining barriers to care engagement that drew upon both theory and prior empirical research in similar settings. Multiple barriers to engagement in care were observed. HIV-related stigma across dimensions of anticipated, internalized and enacted stigma manifested in denial and fears of disclosure,...Continue Reading

Associated Clinical Trials

References

Feb 28, 2002·American Journal of Public Health·Gregory M HerekKeith F Widaman
Apr 13, 2007·AIDS Patient Care and STDs·Chinazo O CunninghamHoward D Cabral
Jun 11, 2009·JAMA : the Journal of the American Medical Association·Carl W Dieffenbach, Anthony S Fauci
Dec 3, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Vikram S GillP Richard Harrigan
Jun 12, 2010·Lancet·Deborah DonnellUNKNOWN Partners in Prevention HSV/HIV Transmission Study Team
Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Jul 21, 2011·Lancet·Salim S Abdool Karim, Quarraisha Abdool Karim
Dec 25, 2013·PloS One·Hasina SamjiUNKNOWN North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of IeDEA
Jul 1, 2015·BMC Infectious Diseases·Baligh R YehiaJudy A Shea
Jan 16, 2016·AIDS and Behavior·Anna V KuznetsovaAnastasia G Amirkhanian
Jul 19, 2016·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team

❮ Previous
Next ❯

Citations

Sep 19, 2019·Revista brasileira de enfermagem·Révia Ribeiro CastroRichardson Augusto Rosendo da Silva
Feb 7, 2020·AIDS·Jennifer CohenWillem Daniel Francois Venter
Jun 27, 2020·Journal of the International AIDS Society·Kathryn DovelSara Yeatman
Sep 4, 2020·AIDS·Barbara A FriedlandUNKNOWN PLHIV Stigma Index 2.0 Study Group
Jul 22, 2019·AIDS and Behavior·Elise D RileyAdam W Carrico
Dec 2, 2019·Journal of Controlled Release : Official Journal of the Controlled Release Society·Stefanie ThalhauserMiriam Breunig
Jan 9, 2021·AIDS and Behavior·Virginia A FonnerSamuel Likindikoki
Aug 28, 2021·International Journal of Environmental Research and Public Health·Nwanneka E OkereGabriela B Gomez
Sep 9, 2021·Journal of the International AIDS Society·Elizabeth M IrunguUNKNOWN Partners Scale-Up Project Team
Oct 13, 2021·African Journal of AIDS Research : AJAR·Edith ApondiPaula Braitstein
Nov 30, 2021·Journal of the International Association of Providers of AIDS Care·Florence MwangwaCarol S Camlin

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT01864683

Software Mentioned

SEARCH

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.