Hurthle cell neoplasms of the thyroid: sonographic appearance and histologic characteristics

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Zeev V MaizlinJacqueline A Brown

Abstract

The purpose of this study was to determine the sonographic features of Hürthle cell neoplasms (HCNs) of the thyroid. We retrospectively analyzed the sonographic appearance of 15 histologically proven HCNs in 15 patients aged 16 to 70 years (mean age, 44 years). Sonographic features that were reviewed included the size and echogenicity of the tumors, the presence of cystic areas or calcifications, and detectable blood flow on color Doppler imaging. Correlation of sonographic findings with pathologic results was performed. The tumors ranged from 0.4 to 7 cm in diameter, but most were less than 3 cm in diameter. Four (27%) of the 15 tumors were homogeneously hypoechoic. Two tumors (13%) were predominantly hypoechoic with isoechoic areas to thyroid parenchyma. Two (13%) neoplasms were isoechoic to thyroid parenchyma. Four (27%) tumors were predominantly isoechoic, containing hypoechoic areas, and 3 (20%) tumors were hyperechoic. Three neoplasms contained cystic components. None of the tumors contained calcifications. One tumor was avascular on Doppler examination. One neoplasm showed only peripheral blood flow. Thirteen tumors showed internal vascularity, 7 of them with peripheral blood flow. Twelve HCNs were benign, and 3 were mal...Continue Reading

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Citations

Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sevim TuranliAbdullah Cetin
Jun 24, 2009·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yurong HongZhiyan Luo
Oct 4, 2011·The Oncologist·Jennifer Cannon
May 18, 2016·The Indian Journal of Surgery·Michael Shawky, Mahmoud Sakr
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Oct 30, 2020·Journal of Clinical Medicine·Dorota Słowińska-KlenckaBożena Popowicz

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