Hyaline cartilage at porta hepatis in extrahepatic biliary atresia: metaplasia or choristoma

Sudanese Journal of Paediatrics
Poonam Elhence, Arvind Sinha

Abstract

We report a case of a 5-month-old child who presented with the features of obstructive jaundice, anaemia and had no associated congenital anomalies. The child was suspected to have biliary atresia on hepatobiliary iminodiacetic acid (HIDA) scan and underwent Kasai portoenterostomy. Microscopic examination of the atretic gallbladder revealed islands of mature hyaline cartilage, lymphoid aggregates and fibrosis. There was an abrupt transition between the cartilage and the adjacent stroma. Only rare case reports have documented this finding with hypothesis ranging from metaplasia occurring secondary to the associated chronic inflammation or whether it is a choristoma. These cases need to be documented to elucidate the pathways of occurrence and may lead to have a better and detailed understanding of the disease process.

References

Feb 20, 2007·Journal of Clinical Pathology·E Altamirano, R Drut
Sep 19, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Yasuyo KashiwagiMasayoshi Kage
Jul 22, 2008·Journal of Pediatric Surgery·Jens StahlschmidtPatricia McClean
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Aug 31, 2013·Orphanet Journal of Rare Diseases·Claus Petersen, Mark Davenport
Jun 9, 2015·Indian Journal of Pediatrics·Mukul VijMohamed Safwan
Jun 13, 2020·Sudanese Journal of Paediatrics·Poonam Elhence, Arvind Sinha

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Jun 13, 2020·Sudanese Journal of Paediatrics·Poonam Elhence, Arvind Sinha

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