PMID: 7541966Aug 1, 1995Paper

Hyaline-cell rich chondroid syringoma. A tumor mimicking malignancy

The American Journal of Surgical Pathology
J A Ferreiro, A G Nascimento

Abstract

We report three cases of chondroid syringoma composed almost entirely of hyaline cells and occurring in the soft tissues. These lesions were confused with a variety of malignant neoplasms, including malignant melanoma, myxoid chondrosarcoma, and alveolar soft part sarcoma. The tumors occurred in two men and one woman aged 37, 75, and 71 years, respectively, and involved the heel, great toe, and face. All cases arose in the subcutaneous tissue or fascial layer and ranged in size from 0.8 to 2.0 cm. The neoplasms were composed of plasmacytoid hyaline cells with variable amounts of myxoid stroma. Two of the chondroid syringomas contained rare duct structures. One contained cartilage lobules but no ducts. All were well circumscribed. Immunohistochemistry showed positive staining for keratin, S-100, and vimentin in all cases. Muscle markers, including desmin, smooth-muscle actin, and muscle-specific actin, were negative. Follow-up has showed no evidence of recurrence or metastasis.

Citations

Feb 4, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Reha YavuzerCem Sezer
Aug 22, 2003·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Nezïh SungurUğur Koçer
Apr 29, 1998·The American Journal of Dermatopathology·M T Fernández-FiguerasJ J Navas-Palacios
Sep 15, 2005·The American Journal of Surgical Pathology·Henry D HaskellSook-Bin Woo
Jul 26, 2011·The American Journal of Dermatopathology·Dmitry V KazakovMichal Michal
Jun 27, 2007·The American Journal of Surgical Pathology·Dmitry V KazakovMichal Michal
Aug 28, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Zev SchulhofDavid Mashadian
Jan 18, 2003·Pathology, Research and Practice·Jorge S Reis-FilhoJosé Manuel Lopes
Sep 1, 1999·Pathology International·T SasaguriY Sasaguri
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Cynthia M MagroMartin C Mihm
May 10, 2002·The British Journal of Dermatology·C MiraccoF Miracco
Aug 24, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A M OliveiraA G Nascimento
Sep 10, 2003·The American Journal of Surgical Pathology·Jason L Hornick, Christopher D M Fletcher
Jan 1, 1997·The American Journal of Surgical Pathology·S E KilpatrickC D Fletcher

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