Hyaluronan-binding properties of human serum hemopexin

FEBS Letters
Z HrkalR Stern

Abstract

Hemopexin, the heme-binding serum glycoprotein, exhibits a complex electrophoretic pattern on two-dimensional immunoelectrophoresis on agarose gels into which hyaluronic acid is incorporated in the first and monospecific anti-hemopexin in the second dimension. This heterogeneity reflects a range of interactions of hemopexin isoforms with hyaluronic acid. Electrophoretic patterns of individual human sera greatly differ in their contents of hyaluronan-interacting hemopexin species. Hemopexin itself has no hyaluronidase activity.

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Citations

Oct 3, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·J R Delanghe, M R Langlois
Jul 10, 2003·Molecular and Cellular Endocrinology·Susan E Stred, Joseph L Messina
May 31, 2007·Natural Product Reports·Marcia R MaukA Grant Mauk
Feb 4, 1999·Journal of Neurochemistry·N MadoreJ P Swerts
Jul 15, 2005·Kidney International·Winston W BakkerJola J Kapojos
Aug 30, 2008·Journal of the American Society of Nephrology : JASN·Rachel LennonMoin A Saleem
Jun 5, 2007·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G E Nugent-DerfusR L Sah
Mar 16, 2011·Protein Science : a Publication of the Protein Society·Marcia R MaukA Grant Mauk
Jul 8, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Gabriel Cara-FuentesEduardo H Garin
Mar 30, 2001·The Journal of Biological Chemistry·V B LokeshwarB L Lokeshwar
Jan 26, 2010·Molecular Biology Reports·Jia-Peng BaoLi-Dong Wu
Nov 30, 2007·Biochemistry·Marcia R MaukA Grant Mauk
Aug 14, 1999·Journal of the American Society of Nephrology : JASN·P K CheungW W Bakker

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