Hybrid fluorescent curcumin loaded zein electrospun nanofibrous scaffold for biomedical applications

Biomedical Materials
Dhandayuthapani BrahatheeswaranD Sakthikumar

Abstract

Nanomedicine utilizes engineered nanodevices and nanostructures for monitoring, repair, construction and control of human biological systems at the molecular level. In this study, we investigated the feasibility and potential of zein nanofiber as a delivery vehicle for curcumin in biomedical applications. By optimizing the electrospinning parameters, ultrafine zein fluorescence nanofibers containing curcumin were developed with interconnected fibrous networks. We found that these nanofibers show an increase in fluorescence due to the incorporation of curcumin. The morphology and material properties of the resulting multifunctional nanofiber including the surface area were examined by a field emission-scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA) and confocal microscopy. The surface area and pore size were characterized by N(2) adsorption-desorption isotherm. SEM and fluorescence images showed that the uniform fibers with smooth surface had an average diameter of about 310 nm. An in vitro degradation study showed significant morphological changes. The in vitro evaluations suggested that the curcumin incorporated zein nanofibers showed sustained release of cur...Continue Reading

References

Aug 1, 1976·Biochemical Pharmacology·O P Sharma
Jan 1, 1992·The Journal of Emergency Medicine·J L McCabeR V Pelligrini
Nov 6, 1986·Journal of Immunological Methods·H TadaK Tsukamoto
Jan 1, 1971·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J C PenhosR Levine
Mar 1, 1994·Photochemistry and Photobiology·C F ChignellT A Dahl
Dec 1, 1993·Bioorganic & Medicinal Chemistry·Z SuiP R Ortiz de Montellano
Dec 15, 1995·Journal of Ethnopharmacology·A ApisariyakulD Buddhasukh
Dec 10, 1999·Journal of Agricultural and Food Chemistry·P S NegiK K Sakariah
Nov 17, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·G S SidhuR K Maheshwari
May 17, 2000·The Journal of Pharmacy and Pharmacology·E J ParkD H Sohn
Dec 7, 2000·Photochemistry and Photobiology·S M KhopdeT Mukherjee
Oct 31, 2003·Biopolymers·Lucimara A ForatoLuiz A Colnago
Jan 24, 2004·Biomaterials·D GopinathR Jayakumar
Mar 3, 2004·Journal of Neuroscience Research·Kenjiro OnoMasahito Yamada
Apr 15, 2004·Journal of Agricultural and Food Chemistry·Lucimara A ForatoLuiz A Colnago
Apr 24, 2004·Science·Marie E EganMichael J Caplan
Jun 15, 2004·Biomaterials·Xinming LiuJ-Y Jin-Ye Wang
Mar 2, 2005·Tissue Engineering·Zuwei MaSeeram Ramakrishna
May 17, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Hua-Jie WangJin-Ye Wang
May 18, 2005·Cancer Letters·Annelyse DuvoixMarc Diederich
Mar 11, 2006·Biomaterials·Shengju GongJin-Ye Wang
Jun 14, 2006·Molecular and Cellular Biochemistry·Manikandan PanchatcharamLonchin Suguna
Aug 3, 2006·Journal of Agricultural and Food Chemistry·Baohua Kong, Youling L Xiong
Aug 31, 2006·International Journal of Pharmaceutics·Zibin GaoDawei Chen
Apr 7, 2007·Journal of Agricultural and Food Chemistry·Blanca Hernández-LedesmaBegoña Bartolomé
Apr 13, 2007·Macromolecular Bioscience·Hongliang JiangKangjie Zhu
Nov 27, 2007·Journal of Tissue Engineering and Regenerative Medicine·Anthony Atala
Dec 22, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dharmendra Jain, R Banerjee
May 7, 2008·Biomedical Materials·Michael McManusGary Bowlin
Jun 26, 2008·Biomacromolecules·Tomasz KowalczykTomasz A Kowalewski
May 29, 2009·Clinical and Experimental Pharmacology & Physiology·Jonathan G MerrellLakshmi S Nair
Jul 3, 2009·Small·Aihui MahamYuehe Lin

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Citations

Jul 6, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Rishi Paliwal, Srinath Palakurthi
Oct 5, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Cecilia Zorzi BuenoAngela Maria Moraes
Dec 9, 2014·International Journal of Molecular Sciences·Elisângela CorradiniEdvani Curti Muniz
Apr 8, 2014·Drug Discovery Today·Daikelly I BraghirolliPatricia Pranke
Apr 3, 2013·Carbohydrate Polymers·Xiao-Zhu SunLi-Min Zhu
Feb 17, 2017·Journal of Biomedical Materials Research. Part a·Merve DemirAldo R Boccaccini
Jun 14, 2017·Critical Reviews in Food Science and Nutrition·Ali AlehosseiniNick Tucker
Nov 6, 2018·Journal of Materials Science. Materials in Medicine·Leila MoradkhannejhadVahid Heydari
Apr 24, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Angela EdwardsNarayan Bhattarai
Nov 2, 2019·Journal of Tissue Engineering and Regenerative Medicine·Jessica Cardenas TurnerTreena L Arinzeh
Oct 15, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Lingli DengHui Zhang
Jul 31, 2020·Critical Reviews in Food Science and Nutrition·Oluwaseun P Bamidele, Mohammad Naushad Emmambux
Nov 9, 2019·Current Pharmaceutical Design·Tatiana Rita de Lima NascimentoLúcio Roberto Cançado Castellano
Jul 7, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Rajendra Kurapati, Ashok M Raichur
Mar 28, 2020·Archives of Physiology and Biochemistry·Elsayed I SalimEhab M M Ali
May 25, 2021·ACS Applied Materials & Interfaces·Wevernilson F de DeusBruno V M Rodrigues
Sep 28, 2017·Journal of Agricultural and Food Chemistry·Peng WenHong Wu
Jun 11, 2019·ACS Applied Materials & Interfaces·Gölnur FakhrullinaRawil Fakhrullin

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