Hybrid SPECT-CT: an additional technique for sentinel node detection of patients with invasive bladder cancer

European Urology
Amir SherifMagnus Thörn

Abstract

To explore the feasibility of performing lymphoscintigraphy combined with computed tomography (CT) for preoperative detection of sentinel lymph nodes in patients with invasive bladder cancer. Six consecutive patients scheduled for radical cystectomy underwent lymphoscintigraphy after transurethral injection of Albures-technetium 99m in the detrusor muscle peritumourally both with planar imaging and with single-photon emission computed tomography/CT (SPECT/CT). CT for anatomic fusion was performed directly after the SPECT/CT and both investigations were combined to a fused image. Radical cystectomy started with extended lymphadenectomy and intraoperative detection of sentinel nodes with both Geiger probe and dye marker. The conventional planar lymphoscintigraphies and the fused SPECT/CT were compared with each other and with the outcome of intraoperative sentinel node detection and final histopathologic analyses. The method allowed anatomically detailed preoperative visualisation of 21 sentinel nodes in five of the six patients, whereas planar pictures only visualised two sentinel nodes in two of six patients. Two patients had lymph node metastases and in the other four the nodes were negative. The combined method visualised all...Continue Reading

References

Jan 1, 1997·Annals of Surgery·D ReintgenM Ross
Oct 1, 1998·The New England Journal of Medicine·D KragP Beitsch
Jul 18, 2001·Annals of Surgical Oncology·O E NiewegB B Kroon
Jan 3, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L KretschmerW Becker
Jan 11, 2003·Science·Rakesh K Jain, Timothy P Padera
Nov 24, 2004·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Arne WagnerThomas Leitha
Dec 18, 2004·Cancer Research·Kari AlitaloErkki Ruoslahti
Sep 1, 2005·European Journal of Nuclear Medicine and Molecular Imaging·O DrieskensL Mortelmans
Oct 6, 2005·European Urology·Fredrik Liedberg, Wiking Månsson

❮ Previous
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Citations

Nov 28, 2008·Der Urologe. Ausg. A·L S FreudenbergA Bockisch
Aug 18, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Giovanni Lucignani
Apr 29, 2011·International Journal of Clinical Oncology·Hiroshi KitamuraTaiji Tsukamoto
May 24, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Neil FairbairnMark Butterworth
Dec 8, 2009·Nuclear Medicine Communications·J P Coffey, J C Hill
Jan 29, 2009·World Journal of Surgical Oncology·Stephen P PovoskiEdward W Martin
Feb 27, 2008·Annals of Surgical Oncology·Kjell DahlMagnus Thörn
Aug 31, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Gad Abikhzer, Zohar Keidar
May 15, 2008·World Journal of Surgery·Iris M C van der PloegOmgo E Nieweg
May 8, 2013·European Urology·Derya TilkiBernard H Bochner
Jan 25, 2008·Gynecologic Oncology·C BenederM D Mueller
Feb 16, 2008·Clinical Radiology·F U Chowdhury, A F Scarsbrook
Oct 2, 2007·European Urology·Alexandre R Zlotta
May 21, 2014·BJU International·Riaz J KarmaliJose A Karam
Feb 24, 2009·Journal of Surgical Oncology·Sharon Sharir, Neil E Fleshner
Sep 3, 2010·Contrast Media & Molecular Imaging·Luis Martí-BonmatíPablo Sopena
Nov 20, 2009·Journal of Surgical Oncology·Lenka VermeerenOmgo E Nieweg
Dec 13, 2006·Seminars in Nuclear Medicine·Daniela B Husarik, Hans C Steinert
Apr 9, 2008·Seminars in Nuclear Medicine·Youngho SeoBruce H Hasegawa
Jun 6, 2009·Seminars in Nuclear Medicine·Andreas BockischTorsten Kuwert
Aug 12, 2014·Journal of Surgical Oncology·B E SchaafsmaA L Vahrmeijer
Jul 15, 2015·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Michael A LissA Karim Kader
Oct 16, 2016·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·O R BrouwerS Horenblas
Mar 6, 2007·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Sean McLaughlinRaj S Pruthi
Sep 26, 2007·Expert Review of Anticancer Therapy·Amir SherifN Peter Wiklund
Mar 17, 2016·World Journal of Nephrology·Tharani MahesanNick Watkin
Feb 9, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Ziauddin Zia SaadJamshed Bomanji
Apr 8, 2016·Clinical Nuclear Medicine·Wojciech PołomMarcin Matuszewski
Nov 21, 2018·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·Ebru SalmanogluMathew L Thakur
Jul 14, 2020·Annals of Nuclear Medicine·Leili ZarifmahmoudiMaryam Salehi
Jul 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Andreas K BuckAlexander Drzezga
May 16, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Lenka VermeerenSimon Horenblas

❮ Previous
Next ❯

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