Hybrid verrucous-squamous cell carcinoma of the ovary with synchronous squamous cell carcinoma of the endometrium

International Journal of Surgical Pathology
Tiffany T FancherJ Alexander Palesty

Abstract

Verrucous carcinoma, a variant of well-differentiated squamous cell carcinoma, is usually described in the literature as arising in the oral cavity, skin, and larynx. The reports on verrucous carcinoma arising in the genital tract, usually originating in the vagina, vulva, or uterine cervix, are few. Verrucous carcinoma arising in the ovary has not been previously reported. In this article, a unique hybrid carcinoma, a large aggressive verrucous carcinoma in combination with squamous carcinoma of the left ovary and synchronously occurring with a squamous cell carcinoma in the endometrium, is presented. This unique case of a hybrid carcinoma includes the first-known case of this type of carcinoma involving the ovary. The negative cervical evaluation findings, together with the histologic patterns of the tumors in the uterus and the ovary, support the conclusion that these 2 carcinomas are synchronous, one arising in the left ovary and the other arising in the uterus.

References

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Jul 1, 1997·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·M R PinsR E Scully
Aug 10, 2000·The Journal of Obstetrics and Gynaecology Research·Y ShidaraT Tanaka

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Citations

Jun 22, 2010·Ophthalmic Plastic and Reconstructive Surgery·Shiu Ting MakRaymond Kwok-Kay Tse

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