Hybridization of pyrrolidinyl peptide nucleic acids and DNA: selectivity, base-pairing specificity, and direction of binding

Organic Letters
Tirayut Vilaivan, Choladda Srisuwannaket

Abstract

[structure: see text] A mixed-base, beta-amino acid containing, pyrrolidinyl peptide nucleic acid (PNA) binds strongly and selectively to complementary DNA in an exclusively antiparallel fashion. The PNA-DNA binding specificity strictly follows the Watson-Crick base-pairing rules.

Citations

Mar 2, 2011·Nucleosides, Nucleotides & Nucleic Acids·Patcharee Ngamwiriyawong, Tirayut Vilaivan
Nov 14, 2014·Artificial Cells, Nanomedicine, and Biotechnology·Nasrin SohrabiAbolfazl Akbarzadeh
Dec 24, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Oraphan WiarachaiVoravee P Hoven
Apr 17, 2010·Chemistry & Biodiversity·Peter E Nielsen
Jun 3, 2008·Biochemical and Biophysical Research Communications·Khatcharin SiriwongSupot Hannongbua
Apr 8, 2015·Nano Letters·Sunatda ArayachukiatSupason Wanichwecharungruang
Feb 11, 2009·Journal of the American Chemical Society·Soo Hyuk ChoiSamuel H Gellman
Jun 24, 2017·Chemical Communications : Chem Comm·Shigetaka NakamuraKenzo Fujimoto
Aug 1, 2015·Organic & Biomolecular Chemistry·Peggy R BohländerHans-Achim Wagenknecht
Oct 7, 2011·Chemistry, an Asian Journal·Chalothorn BoonluaTirayut Vilaivan
Apr 11, 2009·Chemistry : a European Journal·Gaetano AngeliciClaudia Tomasini
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Jan 6, 2007·Organic & Biomolecular Chemistry·Roberta J WorthingtonJason Micklefield
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Aug 1, 2012·ChemistryOpen·Sabrina SeziHans-Achim Wagenknecht
Feb 21, 2013·Organic & Biomolecular Chemistry·Chotima VilaivanTirayut Vilaivan
Sep 24, 2014·Beilstein Journal of Organic Chemistry·Nattawut YotapanTirayut Vilaivan
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Apr 29, 2008·Journal of the American Chemical Society·Soo Hyuk ChoiSamuel H Gellman
Mar 2, 2012·Organic Letters·Woraluk MansawatTirayut Vilaivan
May 30, 2015·Accounts of Chemical Research·Tirayut Vilaivan
Aug 10, 2021·Beilstein Journal of Organic Chemistry·Nikita BrodyaginEriks Rozners
Jun 16, 2015·Bioconjugate Chemistry·Anjan BanerjeeVaijayanti A Kumar
May 24, 2019·Journal of the American Chemical Society·Keiji MurayamaHiroyuki Asanuma
Sep 4, 2021·Analytical and Bioanalytical Chemistry·Nuttapon JirakittiwutThanit Praneenararat
Oct 24, 2007·Journal of the American Chemical Society·Soo Hyuk ChoiSamuel H Gellman

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