PMID: 15366449Sep 16, 2004Paper

Hydro-cellular dressing and silver sulfadiazine. Evaluation of its combination in the treatment of infected skin ulcers

Revista de enfermería
Fernando Martínez CuervoManuel García Toro

Abstract

The authors carried out an observational, descriptive, prospective and multi-centric study on 49 infected lesions which had clinical signs of local infection as well as infection from a positive sprinkler method culture. These lesions were treated over a three week period with argentic sulfadiazine and a semi-permeable dressing; afterward, treatment continued for seven weeks more based on cures in a humid environment by means of a semi-permeable dressing. After three weeks of treatment, two-thirds of these lesions showed a negative exudative culture, the number of strains present in the rest of the cultures diminished to at least half of those present at the start of this study. 15 of these lesions completely closed over during the period of study (mean = 46.73 +/- 22.74 days) and the absolute cicatrisation surface area varied, on average, from 23.46 square cm at the start to 12.39 square cm at the end of this study. In relation to the relative cicatrisation an average reduction of 76.5% (IC 95= (66.85% - 86.2%)) occurred. Variance analysis (ANOVA) over repeated measurements established significant differences (p = 0.001) having a tendency toward a lineal decrease. The authors also found statistically significant differences re...Continue Reading

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