Hydrogen bond migration between molecular sites observed with ultrafast 2D IR chemical exchange spectroscopy.

The Journal of Physical Chemistry. B
Daniel E RosenfeldM D Fayer

Abstract

Hydrogen-bonded complexes between phenol and phenylacetylene are studied using ultrafast two-dimensional infrared (2D IR) chemical exchange spectroscopy. Phenylacetylene has two possible pi hydrogen bonding acceptor sites (phenyl or acetylene) that compete for hydrogen bond donors in solution at room temperature. The OD stretch frequency of deuterated phenol is sensitive to which acceptor site it is bound. The appearance of off-diagonal peaks between the two vibrational frequencies in the 2D IR spectrum reports on the exchange process between the two competitive hydrogen-bonding sites of phenol-phenylacetylene complexes in the neat phenylacetylene solvent. The chemical exchange process occurs in approximately 5 ps and is assigned to direct hydrogen bond migration along the phenylacetylene molecule. Other nonmigration mechanisms are ruled out by performing 2D IR experiments on phenol dissolved in the phenylacetylene/carbon tetrachloride mixed solvent. The observation of direct hydrogen bond migration can have implications for macromolecular systems.

References

Mar 20, 2003·Angewandte Chemie·Emmanuel A MeyerFrançois Diederich
Jun 17, 2004·Journal of the American Chemical Society·Mutasem Omar Sinnokrot, C David Sherrill
Apr 20, 2005·The Journal of Chemical Physics·Sidney P Elmer, Vijay S Pande
Jul 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·Yung Sam Kim, Robin M Hochstrasser
Sep 21, 2005·Accounts of Chemical Research·Jacky W Y Lam, Ben Zhong Tang
Mar 28, 2006·Biophysical Journal·Michael F Hagan, David Chandler
Oct 6, 2006·The Journal of Physical Chemistry. B·Kyungwon KwakM D Fayer
Mar 22, 2007·Journal of the American Chemical Society·Junrong Zheng, Michael D Fayer
Jun 22, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kyungwon KwakM D Fayer
Mar 18, 2008·The Journal of Physical Chemistry. a·Prashant Chandra SinghG Naresh Patwari
May 22, 2008·The Journal of Physical Chemistry. a·Prashant Chandra Singh, G Naresh Patwari
Jun 20, 2008·Proceedings of the National Academy of Sciences of the United States of America·Haruto IshikawaMichael D Fayer
Dec 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·David E MoilanenM D Fayer
Sep 15, 2009·The Journal of Physical Chemistry. B·Daniel E RosenfeldM D Fayer

❮ Previous
Next ❯

Citations

Jun 9, 2011·The Journal of Physical Chemistry. a·Megan C Thielges, Michael D Fayer
Aug 25, 2011·The Journal of Chemical Physics·Emily E Fenn, M D Fayer
Oct 15, 2010·The Journal of Chemical Physics·Michael W NydeggerChristopher M Cheatum
May 23, 2014·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Danijela Vojta, Mario Vazdar
Jul 24, 2015·The Journal of Physical Chemistry. B·Matthew C ZoerbCharles B Harris
Jun 8, 2015·The Journal of Chemical Physics·Tatsuya IshiyamaTahei Tahara
Jul 31, 2013·Journal of Chemical Theory and Computation·Pan WuWeitao Yang
Aug 16, 2015·The Journal of Physical Chemistry Letters·Somnath M Kashid, Sayan Bagchi
Oct 27, 2017·Topics in Current Chemistry·Jan Philip Kraack
Jan 13, 2011·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Surajit MaityG Naresh Patwari
Dec 26, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiaochu DingYadong Wang
Jul 24, 2020·The Journal of Physical Chemistry. B·Christian MalmJohannes Hunger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.