Hydrogen loss from nucleobase nitrogens upon electron attachment to isolated DNA and RNA nucleotide anions

The Journal of Chemical Physics
B LiuS Tomita

Abstract

Electron transfer to isolated nucleotide monoanions in collisions with Na vapor induces hydrogen loss from nitrogen of the transient nucleobase anion. The cross section for this process is linearly correlated with the number of N-H hydrogens and is highest for guanine. The process is much faster than microseconds since only dehydrogenated dianions survived for mass spectrometric detection. The lifetime of the adenosine 5(')-monophospate dianions was measured to be 0.2 ms in an electrostatic ion storage ring but also a longer-lived component with a lifetime of at least 10 ms was identified. Implications of dissociation along the N-H coordinate for a nucleotide in DNA are briefly discussed in terms of Watson-Crick base pairs.

References

Jul 18, 2001·Journal of the American Chemical Society·S S WesolowskiH F Schaefer
Jan 10, 2002·Chemical Reviews·Andreas Dreuw, Lorenz S Cederbaum
Apr 10, 2003·Journal of the American Chemical Society·Michael A HuelsLeon Sanche
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Citations

Feb 16, 2008·Journal of the American Society for Mass Spectrometry·Virgile BernigaudSteen Brøndsted Nielsen
Feb 27, 2008·The Journal of Chemical Physics·B LiuB A Huber
May 11, 2006·Proceedings of the National Academy of Sciences of the United States of America·Maria C LindHenry F Schaefer
Nov 27, 2009·European Journal of Mass Spectrometry·Jean Ann WyerHenning T Schmidt
Sep 26, 2019·Physical Chemistry Chemical Physics : PCCP·Dipayan ChakrabortyDhananjay Nandi
Sep 22, 2012·Chemistry : a European Journal·Yun-xiang PanMingdong Dong
Apr 2, 2009·The Journal of Physical Chemistry. B·N R JenaS Suhai

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