Hydrogen peroxide-producing Lactobacilli in the vaginal flora of pregnant women with preterm labor with intact membranes

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Y H KimJ S Oh

Abstract

To investigate the role of vaginal infection in preterm delivery, we studied characteristics of vaginal discharge related to hydrogen peroxide-producing Lactobacilli. Vaginal specimens were obtained from 66 women with normal pregnancy and 30 women with preterm labor with intact membranes. pH, leukocyte counts on wet smear, and scores by Nugent criteria on Gram stain were measured. Lactobacilli were tested for their production of hydrogen peroxide. Leukocyte levels in wet smears and Nugent scores of Gram-stained smear of women with preterm labor with intact membranes were significantly higher than those of normal pregnant women (P<0.01, P<0.05). Hydrogen peroxide-producing Lactobacilli levels in the vaginal flora of women with preterm labor with intact membranes were significantly lower (P<0.01). Distribution of hydrogen peroxide-producing Lactobacilli in vaginal flora as defense factors for infection may have an important role in the pathophysiology of preterm labor.

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Citations

Jan 24, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Harald Leitich, Herbert Kiss
May 19, 2011·Future Microbiology·Rachel R Spurbeck, Cindy Grove Arvidson
Oct 31, 2013·Archives of Gynecology and Obstetrics·Sandra BorgesPaula Teixeira
Nov 28, 2009·Medical Hypotheses·Usha SrinivasanBetsy Foxman
Aug 19, 2007·European Journal of Oral Sciences·Charlotte Simark-MattssonStig Holm
Jun 22, 2021·Critical Reviews in Food Science and Nutrition·Amin AbbasiAziz Homayouni-Rad

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