Hydrogen Peroxide Production as a Limiting Factor in Xenobiotic Compound Oxidation by Nitrogen-Sufficient Cultures of Bjerkandera sp. Strain BOS55 Overproducing Peroxidases.

Applied and Environmental Microbiology
M J KottermanJ A Field

Abstract

The overproduction of ligninolytic peroxidase by the N-deregulated white rot fungus Bjerkandera sp. strain BOS55 under nitrogen-sufficient conditions had no noteworthy effect on the oxidation of anthracene or the decolorization of the polymeric aromatic dye Poly R-478 in 6-day-old cultures. Only when the endogenous production of H(inf2)O(inf2) was increased by the addition of extra oxygen and glucose could a 2.5-fold increase in the anthracene oxidation rate and a 6-fold increase in the Poly R-478 decolorization rate be observed in high-N cultures with 10- to 35-fold higher peroxidase activities than N-limited cultures. Further increase of the H(inf2)O(inf2) generation rate in high-N cultures with glucose oxidase led to an additional 3.5-fold increase in the anthracene oxidation rate (350 mg liter(sup-1) day(sup-1)) and a 10-fold increase in the Poly R-478 decolorization rate. These results indicate that xenobiotic compound oxidation by white rot fungi cannot be improved by overproducing peroxidases without increasing the endogenous production of H(inf2)O(inf2). The absence of Mn, which decreased the manganese peroxidase titers and increased the lignin peroxidase titers, was associated with up to 95% improvements in the anthrac...Continue Reading

References

Jan 1, 1990·Applied Microbiology and Biotechnology·Y KimuraM Kuwahara
Jul 1, 1992·Applied and Environmental Microbiology·J A FieldJ A de Bont
Sep 1, 1991·Applied and Environmental Microbiology·A B OrthM Tien
Jul 1, 1991·Archives of Biochemistry and Biophysics·J L Popp, T K Kirk
Dec 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·K E HammelW Z Gai
Jan 1, 1987·Annual Review of Microbiology·T K Kirk, R L Farrell
Jun 13, 1995·Biochemistry·A KhindariaS D Aust
Sep 1, 1994·Applied and Environmental Microbiology·D LiM H Gold
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·P J Kersten
Jan 1, 1990·Applied and Environmental Microbiology·P Bonnarme, T W Jeffries
May 1, 1995·Applied and Environmental Microbiology·T MesterJ A Field
Jun 1, 1984·Environmental Science & Technology·R W Walters, R G Luthy

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Citations

Dec 2, 2006·Journal of Basic Microbiology·Ivana EichlerováFrantisek Nerud
Jun 12, 2009·Critical Reviews in Biotechnology·Husain QayyumKulshrestha Yasha
Mar 7, 2013·Applied Microbiology and Biotechnology·Ryota Kataoka, Kazuhiro Takagi
Nov 12, 2005·Applied Microbiology and Biotechnology·Martha Lacayo RomeroBo Mattiasson
Feb 24, 2006·Journal of Industrial Microbiology & Biotechnology·I EichlerováF Nerud
Nov 18, 2020·The Science of the Total Environment·Carolina MerinoMichaela A Dippold
Dec 26, 2001·Chemical Reviews·R ten Have, P J Teunissen
Aug 14, 2010·Environmental Science & Technology·Ryota KataokaYuuki Sato
Dec 1, 1996·Applied and Environmental Microbiology·P J CollinsA Dobson

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