Hydrogen Sulfide and Persulfides Oxidation by Biologically Relevant Oxidizing Species

Antioxidants
Dayana BenchoamBeatriz Alvarez

Abstract

Hydrogen sulfide (H₂S/HS⁻) can be formed in mammalian tissues and exert physiological effects. It can react with metal centers and oxidized thiol products such as disulfides (RSSR) and sulfenic acids (RSOH). Reactions with oxidized thiol products form persulfides (RSSH/RSS⁻). Persulfides have been proposed to transduce the signaling effects of H₂S through the modification of critical cysteines. They are more nucleophilic and acidic than thiols and, contrary to thiols, also possess electrophilic character. In this review, we summarize the biochemistry of hydrogen sulfide and persulfides, focusing on redox aspects. We describe biologically relevant one- and two-electron oxidants and their reactions with H₂S and persulfides, as well as the fates of the oxidation products. The biological implications are discussed.

References

Jan 1, 1977·International Journal of Peptide and Protein Research·G FedericiD Cavallini
Aug 1, 1977·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·M QuintilianiG Gorin
Jan 1, 1992·Annual Review of Pharmacology and Toxicology·R J ReiffensteinS H Roth
Mar 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·W N ValentineR A Brockway
Oct 1, 1986·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·M TambaM Quintiliani
Jan 1, 1987·Methods in Enzymology·J L Wood
Aug 1, 1986·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·J I Toohey
May 1, 1985·Proceedings of the Society for Experimental Biology and Medicine·H KruszynaR P Smith
Jul 11, 1967·Biochimica Et Biophysica Acta·T W Szczepkowski, J L Wood
Jan 1, 1984·Critical Reviews in Toxicology·R O BeauchampD A Andjelkovich
Sep 1, 1980·The Biochemical Journal·T M Florence
Jan 1, 1995·Methods in Enzymology·S A Everett, P Wardman
Apr 20, 1995·Archives of Biochemistry and Biophysics·D G SearcyM J Maroney
Aug 28, 1997·Biochemical and Biophysical Research Communications·R HosokiH Kimura
Apr 29, 1998·Annual Review of Physiology·M K Grieshaber, S Völkel
May 1, 1957·Biochimica Et Biophysica Acta·B SORBO
Apr 1, 1960·Archives of Biochemistry and Biophysics·D CAVALLINIB MONDOVI
Feb 1, 1962·Archives of Biochemistry and Biophysics·D CAVALLINIA SCIOSCIASANTORO
May 25, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yuka Kimura, Hideo Kimura
Jul 17, 2004·Journal of Neurochemistry·Matthew WhitemanPhilip K Moore
Dec 21, 2004·Biochemical and Biophysical Research Communications·Matthew WhitemanPhilip K Moore
Jul 12, 2005·Bioorganic & Medicinal Chemistry Letters·Tonika ChatterjiKent S Gates
Jan 24, 2006·American Journal of Physiology. Lung Cellular and Molecular Physiology·Huili ZhangMadhav Bhatia
Oct 27, 2006·FEMS Microbiology Reviews·Dorothea Kessler
Feb 23, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Marc GoubernFrédéric Bouillaud
Jun 20, 2007·Free Radical Research·Hilde LaggnerStylianos Kapiotis
Sep 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·John W ElrodDavid J Lefer
Mar 12, 2008·Antioxidants & Redox Signaling·Michael J DaviesMartin D Rees
Jun 24, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Saurabh JhaDavid J Lefer
Sep 19, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Julie FurneMichael D Levitt
Oct 16, 2008·Antioxidants & Redox Signaling·Norihiro ShibuyaHideo Kimura
Jun 6, 2009·The Journal of Pharmacology and Experimental Therapeutics·Jand Venes R MedeirosMarcellus H L P Souza
Jul 18, 2009·Circulation Research·John W CalvertDavid J Lefer
Sep 22, 2009·Canadian Journal of Physiology and Pharmacology·Liping FangXinmin Liu

❮ Previous
Next ❯

Citations

May 16, 2019·Journal of Experimental Botany·Cecilia GotorLuis C Romero
May 7, 2020·Antioxidants & Redox Signaling·Gabriel Gojon, Guillermo A Morales
Jul 24, 2020·The Journal of Biological Chemistry·Brenna J C Walsh, David P Giedroc
Aug 2, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sergei V MakarovAnna S Makarova
Apr 3, 2020·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Joseph K MaddryVikhyat S Bebarta
Aug 18, 2020·Antioxidants & Redox Signaling·Colin G Miller, Edward E Schmidt
Feb 6, 2020·Essays in Biochemistry·Dayana BenchoamBeatriz Alvarez
Dec 1, 2020·The New Phytologist·Rosario PantalenoCarlos García-Mata
Dec 18, 2020·Frontiers in Cellular and Infection Microbiology·Md Aejazur RahmanAdrie J C Steyn
Jan 24, 2021·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Kelly AscençãoCsaba Szabo
Jan 23, 2021·Free Radical Biology & Medicine·Hannah Petraitis KuschmanDouglas D Thomas
Feb 23, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Peng-Hao Hsu, Adah Almutairi
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rezeda A IshkaevaTimur I Abdullin
May 22, 2021·Archives of Biochemistry and Biophysics·Jiechun ZhuGuangdong Yang
Jun 12, 2021·ACS Chemical Biology·Kearsley M Dillon, John B Matson
Jun 25, 2021·Antioxidants & Redox Signaling·Yingying WangMing Xian
Aug 23, 2019·Journal of the American Chemical Society·Micah T NelpJohn T Groves
Mar 12, 2020·Current Medicinal Chemistry·Salvatore FuschilloMauro Maniscalco
Jan 19, 2021·ACS Biomaterials Science & Engineering·Jitendra PantHitesh Handa
Aug 25, 2021·Nitric Oxide : Biology and Chemistry·Jiechun Zhu, Guangdong Yang
Nov 18, 2021·American Journal of Physiology. Cell Physiology·Adriana M Fresquez, Carl White

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Biochemistry and Biophysics
Ernesto CuevasantaBeatriz Alvarez
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
Lucía TurellBeatriz Alvarez
© 2022 Meta ULC. All rights reserved