Hydrogen Sulfide: From a Toxic Molecule to a Key Molecule of Cell Life

Antioxidants
Angeles ArocaLuis C Romero

Abstract

Hydrogen sulfide (H2S) has always been considered toxic, but a huge number of articles published more recently showed the beneficial biochemical properties of its endogenous production throughout all regna. In this review, the participation of H2S in many physiological and pathological processes in animals is described, and its importance as a signaling molecule in plant systems is underlined from an evolutionary point of view. H2S quantification methods are summarized and persulfidation is described as the underlying mechanism of action in plants, animals and bacteria. This review aims to highlight the importance of its crosstalk with other signaling molecules and its fine regulation for the proper function of the cell and its survival.

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Citations

Sep 19, 2020·Journal of Experimental Botany·Francisco J CorpasJosé M Palma
Dec 1, 2020·The New Phytologist·Rosario PantalenoCarlos García-Mata
Mar 23, 2021·Oxidative Medicine and Cellular Longevity·Huaxing ZhangYuming Wu
Apr 17, 2021·Physiologia Plantarum·Meenakshi Thakur, Anjali Anand
May 13, 2021·Proceedings of the National Academy of Sciences of the United States of America·Angeles ArocaDiane C Bassham
Jun 3, 2021·Antioxidants·Sofia S MendesLígia M Saraiva
Jun 3, 2021·Journal of Experimental Botany·Angeles ArocaCecilia Gotor
Aug 28, 2021·Cells·Antonio Rivas-DomínguezManuel Luis Orta

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Methods Mentioned

BETA
environmental stress
biosensor
acetylation

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