Hydrological variation modulates pharmaceutical levels and biofilm responses in a Mediterranean river

The Science of the Total Environment
Victoria OsorioDamià Barceló

Abstract

The Llobregat is a Mediterranean river that is severely impacted by anthropogenic pressures. It is characterized by high flow variability which modulates its chemical and biological status. The present work evaluates the effects of flow changes on the concentration of pharmaceutically active compounds (PhACs) and their relationship to cellular parameters of river biofilms. To this end, at two selected sampling sites at the lower course of the Llobregat river, surface water samples were collected twice a week over two hydrologically different periods exhibiting low and high river flows. Higher levels of PhACs were detected at the downstream sampling site. Irrespective of the flow regime, analgesics, anti-inflammatories and lipid regulators were the most abundant substances at both sampling sites with total concentrations of up to 1,000 ng/L and 550 ng/L at the upstream and downstream sites, respectively. Antibiotics (fluoroquinolones) and psychiatric treatment drugs were also detected at high levels in the second campaign achieving concentrations of up to 500 ng/L. The principal component analysis (PCA) performed with the PhACs concentrations of the two campaigns revealed differences in the various therapeutic groups depending o...Continue Reading

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Citations

Jul 22, 2014·The Science of the Total Environment·N De Castro-CatalàJ L Riera
Dec 18, 2014·Environmental Science and Pollution Research International·Mariele B CampanhaPedro S Fadini
Aug 12, 2016·The Science of the Total Environment·Alba Arenas-SánchezMarco Vighi
Dec 30, 2017·Environmental Science and Pollution Research International·Brice Reoyo-PratsCarmen Palacios
Nov 20, 2015·Frontiers in Microbiology·José L BalcázarCarles M Borrego
Aug 9, 2018·The Science of the Total Environment·Ladislav MandaricSergi Sabater
Jun 27, 2019·Environmental Science & Technology·Davide Vione, Andrea Scozzaro

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