Hydrosalpinx treated with extended doxycycline does not compromise the success of in vitro fertilization

Fertility and Sterility
B S HurstW D Schlaff

Abstract

To determine if extended treatment with doxycycline before and after an in vitro fertilization (IVF) procedure can minimize the detrimental effect of a hydrosalpinx. Retrospective analysis. University IVF program. Patients undergoing IVF, including 17 with a hydrosalpinx, 25 with adhesions or proximal tubal occlusion, and 22 with endometriosis or unexplained infertility. Women with a documented hydrosalpinx were prescribed doxycycline 100 mg twice daily starting 1 week before expected retrieval and continued until 6 days after retrieval. No antibiotics were prescribed in the other groups. Implantation rates and IVF outcomes. Implantation rates were 30% for the doxycycline-treated group of patients with a hydrosalpinx, 27% for the group with tubal occlusion/adhesion, and 24% for the group with endometriosis or unexplained infertility. Eight (47%) of 17 patients with a hydrosalpinx had a live birth, compared with 11 (44%) of 25 for the group with tubal occlusion/adhesion and 12 (55%) of 22 for the group with endometriosis/unexplained infertility. There were no differences between the groups in patient age, number of oocytes retrieved, fertilization rate, or number of blastomeres of the transferred embryos. No detrimental effect o...Continue Reading

References

Mar 1, 1996·Human Reproduction·F I ShararaJ T Queenan
Apr 9, 1998·Fertility and Sterility·A C Nackley, S J Muasher

❮ Previous
Next ❯

Citations

Jul 13, 2007·Current Opinion in Obstetrics & Gynecology·Annika Strandell
Oct 30, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Juan Lorente GonzálezJosé Eduardo Arjona Berral
Aug 3, 2010·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Usama M Fouda, Ahmed M Sayed
Jun 30, 2004·Human Fertility : Journal of the British Fertility Society·Emma Sowerby, John Parsons
Feb 15, 2007·Reproductive Biomedicine Online·B OzmenS Al-Hasani
Nov 26, 2008·Fertility and Sterility·UNKNOWN Practice Committee of American Society for Reproductive Medicine in collaboration with Society of Reproductive Surgeons
Mar 12, 2008·Fertility and Sterility·Sérgio Reis SoaresCarlos Simón
Oct 2, 2007·Gynécologie, obstétrique & fertilité·V VernaeveA Pellicer
Jan 18, 2006·Fertility and Sterility·Ricardo Francalacci SavarisCláudio Galleano Zettler
Aug 10, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Olivier ChanellesChristophe Poncelet
Sep 10, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Guillaume LegendreHervé Fernandez
Mar 23, 2017·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A DaniilidisE Assimakopoulos
May 10, 2017·Systems Biology in Reproductive Medicine·Hongchu BaoCuifang Hao
Jan 6, 2006·Obstetrics and Gynecology·Bradley J Van Voorhis
Feb 12, 2005·Human Reproduction·Louis Chukwuemeka AjonumaHsiao Chang Chan
Nov 18, 2008·The Journal of Obstetrics and Gynaecology Research·Louis Chukwuemeka AjonumaHsiao Chang Chan
Aug 13, 2005·Human Reproduction·Annika StrandellIngemar Eckerlund

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.