Hydrostatic versus oleic acid-induced pulmonary edema: high-resolution computed tomography findings in the pig lung

Academic Radiology
J G ImY S Oh

Abstract

We evaluated the differences between combined hydrostatic and hypervolemic edema and oleic acid-induced edema on high-resolution computed tomography (HRCT) scans. Twelve anesthetized and ventilated pigs were studied. Hydrostatic edema was induced by ligation of the abdominal aorta and infusion of normal saline (n = 4); permeability edema was induced by intravenous injection of oleic acid (n = 4). Four pigs were studied as normal controls. Serial scans were obtained before and after induction of edema at a constant position in the caudal lobe of the lung. The distribution of edema was assessed visually. Cross-sectional areas (CSAs) of the pulmonary artery and vein were measured both at the lobar and segmental levels. Gravity-dependent opacity, peribronchovascular fluid collection, prominent centrilobular core, thickening of the interlobular septa, and air-space consolidation at the dependent site were the sequential HRCT findings of hydrostatic edema. Randomly distributed, diffuse patchy high attenuation areas with a tendency for predilection in the subpleural and peripheral areas of the secondary lobule were the findings of oleic acid-induced edema. Hydrostatic edema increased the mean CSAs of the lobular vein by 137.8% +/- 78....Continue Reading

References

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Citations

Apr 26, 2013·Cornea·Liqiang WangDaniel S Kohane
May 29, 2001·Radiology·P ScilliaP A Gevenois
Mar 8, 2005·Critical Reviews in Computed Tomography·P ScilliaP A Gevenois

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